The Intratumoral Distribution of Radiolabeled 177Lu-BR96 Monoclonal Antibodies Changes in Relation to Tumor Histology over Time in a Syngeneic Rat Colon Carcinoma Model.
(2013) In Journal of Nuclear Medicine 54(8). p.1404-1410- Abstract
- The therapeutic effect of radioimmunotherapy depends on the distribution of the absorbed dose in relation to viable cancer cells within the tumor, which in turn is a function of the activity distribution. The aim of this study was to investigate the distribution of (177)Lu-DOTA-BR96 monoclonal antibodies targeting the Lewis Y antigen over 7 d using a syngeneic rat model of colon carcinoma.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3912939
- author
- Örbom, Anders LU ; Eriksson, Sophie LU ; Elgström, Erika LU ; Ohlsson, Tomas G LU ; Nilsson, Rune LU ; Tennvall, Jan LU and Strand, Sven-Erik LU
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Nuclear Medicine
- volume
- 54
- issue
- 8
- pages
- 1404 - 1410
- publisher
- Society of Nuclear Medicine
- external identifiers
-
- wos:000322692400054
- pmid:23804328
- scopus:84876839931
- pmid:23804328
- ISSN
- 0161-5505
- DOI
- 10.2967/jnumed.112.117028
- language
- English
- LU publication?
- yes
- id
- 78f71df6-aba7-4a38-9f7a-75ba155939b9 (old id 3912939)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/23804328?dopt=Abstract
- date added to LUP
- 2016-04-01 11:06:46
- date last changed
- 2022-01-26 05:27:44
@article{78f71df6-aba7-4a38-9f7a-75ba155939b9, abstract = {{The therapeutic effect of radioimmunotherapy depends on the distribution of the absorbed dose in relation to viable cancer cells within the tumor, which in turn is a function of the activity distribution. The aim of this study was to investigate the distribution of (177)Lu-DOTA-BR96 monoclonal antibodies targeting the Lewis Y antigen over 7 d using a syngeneic rat model of colon carcinoma.}}, author = {{Örbom, Anders and Eriksson, Sophie and Elgström, Erika and Ohlsson, Tomas G and Nilsson, Rune and Tennvall, Jan and Strand, Sven-Erik}}, issn = {{0161-5505}}, language = {{eng}}, number = {{8}}, pages = {{1404--1410}}, publisher = {{Society of Nuclear Medicine}}, series = {{Journal of Nuclear Medicine}}, title = {{The Intratumoral Distribution of Radiolabeled 177Lu-BR96 Monoclonal Antibodies Changes in Relation to Tumor Histology over Time in a Syngeneic Rat Colon Carcinoma Model.}}, url = {{https://lup.lub.lu.se/search/files/2390625/4144958.pdf}}, doi = {{10.2967/jnumed.112.117028}}, volume = {{54}}, year = {{2013}}, }