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On the potential of human sinus cavity diagnostics using diode laser gas spectroscopy

Persson, Linda LU ; Svanberg, Katarina LU and Svanberg, Sune LU (2006) In Applied Physics B 82. p.313-317
Abstract
A method for studying human sinus cavities and inflammation status is described. Diode laser spectroscopy of molecular oxygen gas in the cavity is performed at 760 nm through the strongly scattering facial tissue in a backscattering geometry. Model experiments on tissue-like scattering plastics were made to elucidate the possible penetration depths and the expected signal levels. Measurements on the frontal sinuses of a healthy volunteer verify the viability of the technique. The potential for dynamic gas measurements of the possible occlusion of the channels connecting the sinuses with the nasopharyngeal cavity are discussed, and demonstrated in model experiments using a gas with a composition different from that of the ambient air.... (More)
A method for studying human sinus cavities and inflammation status is described. Diode laser spectroscopy of molecular oxygen gas in the cavity is performed at 760 nm through the strongly scattering facial tissue in a backscattering geometry. Model experiments on tissue-like scattering plastics were made to elucidate the possible penetration depths and the expected signal levels. Measurements on the frontal sinuses of a healthy volunteer verify the viability of the technique. The potential for dynamic gas measurements of the possible occlusion of the channels connecting the sinuses with the nasopharyngeal cavity are discussed, and demonstrated in model experiments using a gas with a composition different from that of the ambient air. Extensions to other biomedical diagnostics arenas are discussed. The results obtained suggest that a complementary method for real-time and non-intrusive medical diagnostics using compact instrumentation could be developed. (Less)
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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Applied Physics B
volume
82
pages
313 - 317
publisher
Springer
external identifiers
  • wos:000234571900022
  • scopus:30444442391
ISSN
0946-2171
DOI
10.1007/s00340-005-1968-1
language
English
LU publication?
yes
id
5ee08a49-4381-4aff-835b-08f5eb934ebe (old id 795958)
date added to LUP
2016-04-01 11:40:57
date last changed
2021-09-29 05:05:33
@article{5ee08a49-4381-4aff-835b-08f5eb934ebe,
  abstract     = {A method for studying human sinus cavities and inflammation status is described. Diode laser spectroscopy of molecular oxygen gas in the cavity is performed at 760 nm through the strongly scattering facial tissue in a backscattering geometry. Model experiments on tissue-like scattering plastics were made to elucidate the possible penetration depths and the expected signal levels. Measurements on the frontal sinuses of a healthy volunteer verify the viability of the technique. The potential for dynamic gas measurements of the possible occlusion of the channels connecting the sinuses with the nasopharyngeal cavity are discussed, and demonstrated in model experiments using a gas with a composition different from that of the ambient air. Extensions to other biomedical diagnostics arenas are discussed. The results obtained suggest that a complementary method for real-time and non-intrusive medical diagnostics using compact instrumentation could be developed.},
  author       = {Persson, Linda and Svanberg, Katarina and Svanberg, Sune},
  issn         = {0946-2171},
  language     = {eng},
  pages        = {313--317},
  publisher    = {Springer},
  series       = {Applied Physics B},
  title        = {On the potential of human sinus cavity diagnostics using diode laser gas spectroscopy},
  url          = {https://lup.lub.lu.se/search/ws/files/2592877/2370736.pdf},
  doi          = {10.1007/s00340-005-1968-1},
  volume       = {82},
  year         = {2006},
}