Imaging in cell-based therapy for neurodegenerative diseases.
(2005) In European Journal of Nuclear Medicine and Molecular Imaging 32(Suppl 2). p.417-434- Abstract
- Fetal cell transplantation for the treatment of Parkinsonrsquos and Huntingtonrsquos diseases has been developed over the past two decades and is now in early clinical testing phase. Direct assessment of the graftrsquos survival, integration into the host brain and impact on neuronal functions requires advanced in vivo neuroimaging techniques. Owing to its high sensitivity, positron emission tomography is today the most widely used tool to evaluate the viability and function of the transplanted tissue in the brain. Nuclear magnetic resonance techniques are opening new possibilities for imaging neurochemical events in the brain. The ultimate goal will be to use the combination of multiple imaging modalities for complete functional... (More)
- Fetal cell transplantation for the treatment of Parkinsonrsquos and Huntingtonrsquos diseases has been developed over the past two decades and is now in early clinical testing phase. Direct assessment of the graftrsquos survival, integration into the host brain and impact on neuronal functions requires advanced in vivo neuroimaging techniques. Owing to its high sensitivity, positron emission tomography is today the most widely used tool to evaluate the viability and function of the transplanted tissue in the brain. Nuclear magnetic resonance techniques are opening new possibilities for imaging neurochemical events in the brain. The ultimate goal will be to use the combination of multiple imaging modalities for complete functional monitoring of the repair processes in the central nervous system. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/148191
- author
- Kirik, Deniz LU ; Breysse, Nathalie LU ; Björklund, Tomas LU ; Besret, Laurent and Hantraye, Philippe
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Huntingtonrsquos disease, Parkinsonrsquos disease, Cell transplantation, Positron emission tomography, Magnetic resonance imaging
- in
- European Journal of Nuclear Medicine and Molecular Imaging
- volume
- 32
- issue
- Suppl 2
- pages
- 417 - 434
- publisher
- Springer
- external identifiers
-
- wos:000203011200007
- scopus:29144503167
- ISSN
- 1619-7070
- DOI
- 10.1007/s00259-005-1909-6
- language
- English
- LU publication?
- yes
- id
- 798bfff4-8fd9-4df7-94a0-b34915cfdb12 (old id 148191)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16267643&dopt=Abstract
- date added to LUP
- 2016-04-01 12:13:07
- date last changed
- 2022-01-27 00:33:05
@article{798bfff4-8fd9-4df7-94a0-b34915cfdb12,
abstract = {{Fetal cell transplantation for the treatment of Parkinsonrsquos and Huntingtonrsquos diseases has been developed over the past two decades and is now in early clinical testing phase. Direct assessment of the graftrsquos survival, integration into the host brain and impact on neuronal functions requires advanced in vivo neuroimaging techniques. Owing to its high sensitivity, positron emission tomography is today the most widely used tool to evaluate the viability and function of the transplanted tissue in the brain. Nuclear magnetic resonance techniques are opening new possibilities for imaging neurochemical events in the brain. The ultimate goal will be to use the combination of multiple imaging modalities for complete functional monitoring of the repair processes in the central nervous system.}},
author = {{Kirik, Deniz and Breysse, Nathalie and Björklund, Tomas and Besret, Laurent and Hantraye, Philippe}},
issn = {{1619-7070}},
keywords = {{Huntingtonrsquos disease; Parkinsonrsquos disease; Cell transplantation; Positron emission tomography; Magnetic resonance imaging}},
language = {{eng}},
number = {{Suppl 2}},
pages = {{417--434}},
publisher = {{Springer}},
series = {{European Journal of Nuclear Medicine and Molecular Imaging}},
title = {{Imaging in cell-based therapy for neurodegenerative diseases.}},
url = {{https://lup.lub.lu.se/search/files/2831746/625169.pdf}},
doi = {{10.1007/s00259-005-1909-6}},
volume = {{32}},
year = {{2005}},
}