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Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control

Pollack, Samuela ; Groop, Leif LU ; Ahlqvist, Emma LU ; Lyssenko, Valeriya LU ; Agardh, Elisabet LU and Sobrin, Lucia (2019) In Diabetes 68(2). p.441-456
Abstract
To identify genetic variants associated with diabetic retinopathy (DR), we performed a large multiethnic genome-wide association study. Discovery included eight European cohorts (n = 3,246) and seven African American cohorts (n = 2,611). We meta-analyzed across cohorts using inverse-variance weighting, with and without liability threshold modeling of glycemic control and duration of diabetes. Variants with a P value
Please use this url to cite or link to this publication:
author
; ; ; ; and
author collaboration
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Diabetes
volume
68
issue
2
pages
16 pages
publisher
American Diabetes Association Inc.
external identifiers
  • scopus:85060253807
  • pmid:30487263
ISSN
1939-327X
DOI
10.2337/db18-0567
language
English
LU publication?
yes
additional info
Export Date: 28 January 2019
id
798cc904-2670-480c-9ae9-4a1014d8df6f
date added to LUP
2019-01-28 13:13:34
date last changed
2024-05-14 00:42:54
@article{798cc904-2670-480c-9ae9-4a1014d8df6f,
  abstract     = {{To identify genetic variants associated with diabetic retinopathy (DR), we performed a large multiethnic genome-wide association study. Discovery included eight European cohorts (n = 3,246) and seven African American cohorts (n = 2,611). We meta-analyzed across cohorts using inverse-variance weighting, with and without liability threshold modeling of glycemic control and duration of diabetes. Variants with a P value}},
  author       = {{Pollack, Samuela and Groop, Leif and Ahlqvist, Emma and Lyssenko, Valeriya and Agardh, Elisabet and Sobrin, Lucia}},
  issn         = {{1939-327X}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{441--456}},
  publisher    = {{American Diabetes Association Inc.}},
  series       = {{Diabetes}},
  title        = {{Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control}},
  url          = {{http://dx.doi.org/10.2337/db18-0567}},
  doi          = {{10.2337/db18-0567}},
  volume       = {{68}},
  year         = {{2019}},
}