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Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control

, ; Pollack, Samuela; Groop, Leif LU ; Ahlqvist, Emma LU ; Lyssenko, Valeriya LU ; Agardh, Elisabet LU and Sobrin, Lucia (2019) In Diabetes 68(2). p.441-456
Abstract
To identify genetic variants associated with diabetic retinopathy (DR), we performed a large multiethnic genome-wide association study. Discovery included eight European cohorts (n = 3,246) and seven African American cohorts (n = 2,611). We meta-analyzed across cohorts using inverse-variance weighting, with and without liability threshold modeling of glycemic control and duration of diabetes. Variants with a P value
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Diabetes
volume
68
issue
2
pages
16 pages
publisher
American Diabetes Association Inc.
external identifiers
  • scopus:85060253807
ISSN
1939-327X
DOI
10.2337/db18-0567
language
English
LU publication?
yes
id
798cc904-2670-480c-9ae9-4a1014d8df6f
date added to LUP
2019-01-28 13:13:34
date last changed
2019-02-27 05:11:16
@article{798cc904-2670-480c-9ae9-4a1014d8df6f,
  abstract     = {To identify genetic variants associated with diabetic retinopathy (DR), we performed a large multiethnic genome-wide association study. Discovery included eight European cohorts (n = 3,246) and seven African American cohorts (n = 2,611). We meta-analyzed across cohorts using inverse-variance weighting, with and without liability threshold modeling of glycemic control and duration of diabetes. Variants with a P value },
  author       = {,  and Pollack, Samuela and Groop, Leif and Ahlqvist, Emma and Lyssenko, Valeriya and Agardh, Elisabet and Sobrin, Lucia},
  issn         = {1939-327X},
  language     = {eng},
  number       = {2},
  pages        = {441--456},
  publisher    = {American Diabetes Association Inc.},
  series       = {Diabetes},
  title        = {Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control},
  url          = {http://dx.doi.org/10.2337/db18-0567},
  volume       = {68},
  year         = {2019},
}