Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control
(2019) In Diabetes 68(2). p.441-456- Abstract
- To identify genetic variants associated with diabetic retinopathy (DR), we performed a large multiethnic genome-wide association study. Discovery included eight European cohorts (n = 3,246) and seven African American cohorts (n = 2,611). We meta-analyzed across cohorts using inverse-variance weighting, with and without liability threshold modeling of glycemic control and duration of diabetes. Variants with a P value
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/798cc904-2670-480c-9ae9-4a1014d8df6f
- author
- Pollack, Samuela ; Groop, Leif LU ; Ahlqvist, Emma LU ; Lyssenko, Valeriya LU ; Agardh, Elisabet LU and Sobrin, Lucia
- author collaboration
- organization
- publishing date
- 2019
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Diabetes
- volume
- 68
- issue
- 2
- pages
- 16 pages
- publisher
- American Diabetes Association Inc.
- external identifiers
-
- scopus:85060253807
- pmid:30487263
- ISSN
- 1939-327X
- DOI
- 10.2337/db18-0567
- language
- English
- LU publication?
- yes
- additional info
- Export Date: 28 January 2019
- id
- 798cc904-2670-480c-9ae9-4a1014d8df6f
- date added to LUP
- 2019-01-28 13:13:34
- date last changed
- 2024-05-14 00:42:54
@article{798cc904-2670-480c-9ae9-4a1014d8df6f, abstract = {{To identify genetic variants associated with diabetic retinopathy (DR), we performed a large multiethnic genome-wide association study. Discovery included eight European cohorts (n = 3,246) and seven African American cohorts (n = 2,611). We meta-analyzed across cohorts using inverse-variance weighting, with and without liability threshold modeling of glycemic control and duration of diabetes. Variants with a P value}}, author = {{Pollack, Samuela and Groop, Leif and Ahlqvist, Emma and Lyssenko, Valeriya and Agardh, Elisabet and Sobrin, Lucia}}, issn = {{1939-327X}}, language = {{eng}}, number = {{2}}, pages = {{441--456}}, publisher = {{American Diabetes Association Inc.}}, series = {{Diabetes}}, title = {{Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control}}, url = {{http://dx.doi.org/10.2337/db18-0567}}, doi = {{10.2337/db18-0567}}, volume = {{68}}, year = {{2019}}, }