Vascular disease, hypoxia and consequences
Kalaria, Raj ; Englund, Elisabet LU
and Ferrer, Isidro
(2024)
1.
p.75-243
- Abstract
The central nervous system (CNS) relies on an uninterrupted supply of oxygenated blood, glucose and nutrients for efficient function. Transportation of these fuels is vitally dependent on adequate blood flow through patent brain vessels with the capacity to respond readily to metabolic demands. If the oxygen or glucose content or the flow of blood falls below the level needed to maintain nervous tissue viability, this results in a series of acute and long-term changes within the brain parenchyma. The removal of metabolic wastes such as lactate by venous drainage is also vital for cerebral function.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/7995f60d-71b5-48d4-895b-bc755fe22558
- author
- Kalaria, Raj
; Englund, Elisabet
LU
and Ferrer, Isidro
- organization
- publishing date
- 2024-01-01
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- host publication
- Greenfield's Neuropathology, Tenth Edition : Volume 1-2 - Volume 1-2
- volume
- 1
- pages
- 169 pages
- publisher
- CRC Press/Balkema
- external identifiers
-
- scopus:85210674781
- ISBN
- 9780367895082
- 9781000879889
- DOI
- 10.1201/9781003389699-10
- language
- English
- LU publication?
- yes
- id
- 7995f60d-71b5-48d4-895b-bc755fe22558
- date added to LUP
- 2025-01-21 14:40:49
- date last changed
- 2025-07-09 04:27:34
@inbook{7995f60d-71b5-48d4-895b-bc755fe22558,
abstract = {{<p>The central nervous system (CNS) relies on an uninterrupted supply of oxygenated blood, glucose and nutrients for efficient function. Transportation of these fuels is vitally dependent on adequate blood flow through patent brain vessels with the capacity to respond readily to metabolic demands. If the oxygen or glucose content or the flow of blood falls below the level needed to maintain nervous tissue viability, this results in a series of acute and long-term changes within the brain parenchyma. The removal of metabolic wastes such as lactate by venous drainage is also vital for cerebral function.</p>}},
author = {{Kalaria, Raj and Englund, Elisabet and Ferrer, Isidro}},
booktitle = {{Greenfield's Neuropathology, Tenth Edition : Volume 1-2}},
isbn = {{9780367895082}},
language = {{eng}},
month = {{01}},
pages = {{75--243}},
publisher = {{CRC Press/Balkema}},
title = {{Vascular disease, hypoxia and consequences}},
url = {{http://dx.doi.org/10.1201/9781003389699-10}},
doi = {{10.1201/9781003389699-10}},
volume = {{1}},
year = {{2024}},
}