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Severe diphtheria with neurologic and myocardial involvement in a Swedish patient : A case report

Skogmar, Sten LU and Tham, Johan LU (2018) In BMC Infectious Diseases 18(1).
Abstract

Background: Diphtheria is caused by Corynebacterium diphtheriae. Although waning in incidence diphtheria can cause severe disease as in this rare Swedish case with several complications. Case presentation: A 55-year old male presented to the emergency room with severe respiratory symptoms and greyish membranes in the airways, which turned positive for C. diphtheriae. He was put on ventilator support and remained hospitalized for three months. During care he developed myocarditis and severe neurological disease and he was also co-infected with tuberculosis. The patient was discharged with a favorable outcome. Conclusions: Diphtheria should be suspected in patients with life-threatening pneumonia especially if the patient has a history of... (More)

Background: Diphtheria is caused by Corynebacterium diphtheriae. Although waning in incidence diphtheria can cause severe disease as in this rare Swedish case with several complications. Case presentation: A 55-year old male presented to the emergency room with severe respiratory symptoms and greyish membranes in the airways, which turned positive for C. diphtheriae. He was put on ventilator support and remained hospitalized for three months. During care he developed myocarditis and severe neurological disease and he was also co-infected with tuberculosis. The patient was discharged with a favorable outcome. Conclusions: Diphtheria should be suspected in patients with life-threatening pneumonia especially if the patient has a history of travelling. Our patient was not treated with diphtheria anti-toxin (DAT) which may have contributed to the severity of the disease.

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organization
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type
Contribution to journal
publication status
published
subject
keywords
Corynebacterium diphtheriae, Diphtheria, Immunization, Myocarditis, Neurological manifestations, Respiratory disease, Tuberculosis
in
BMC Infectious Diseases
volume
18
issue
1
publisher
BioMed Central
external identifiers
  • scopus:85050750329
ISSN
1471-2334
DOI
10.1186/s12879-018-3264-9
language
English
LU publication?
yes
id
79a316ea-b9d0-419c-ae8e-b88326150ef2
date added to LUP
2018-08-16 16:04:49
date last changed
2018-11-21 21:41:08
@article{79a316ea-b9d0-419c-ae8e-b88326150ef2,
  abstract     = {<p>Background: Diphtheria is caused by Corynebacterium diphtheriae. Although waning in incidence diphtheria can cause severe disease as in this rare Swedish case with several complications. Case presentation: A 55-year old male presented to the emergency room with severe respiratory symptoms and greyish membranes in the airways, which turned positive for C. diphtheriae. He was put on ventilator support and remained hospitalized for three months. During care he developed myocarditis and severe neurological disease and he was also co-infected with tuberculosis. The patient was discharged with a favorable outcome. Conclusions: Diphtheria should be suspected in patients with life-threatening pneumonia especially if the patient has a history of travelling. Our patient was not treated with diphtheria anti-toxin (DAT) which may have contributed to the severity of the disease.</p>},
  articleno    = {359},
  author       = {Skogmar, Sten and Tham, Johan},
  issn         = {1471-2334},
  keyword      = {Corynebacterium diphtheriae,Diphtheria,Immunization,Myocarditis,Neurological manifestations,Respiratory disease,Tuberculosis},
  language     = {eng},
  month        = {07},
  number       = {1},
  publisher    = {BioMed Central},
  series       = {BMC Infectious Diseases},
  title        = {Severe diphtheria with neurologic and myocardial involvement in a Swedish patient : A case report},
  url          = {http://dx.doi.org/10.1186/s12879-018-3264-9},
  volume       = {18},
  year         = {2018},
}