Diagnostic stability in adolescent onset psychotic disorders
(2003) In European Child & Adolescent Psychiatry 12(1). p.15-22- Abstract
- The purpose was to examine the long-term stability of a diagnosis of psychotic disorder in adolescence and to focus on diagnostic change over time. A total of 88 patients with a first episode of early onset psychosis (before 19 years) were followed up an average of 10.5 years (range 5.1-18.2) after admission. This report includes the 68 patients who could be traced and interviewed with the Positive and Negative Symptom Scale and lifetime Structured Clinical Interview for DSM-IV diagnosis. An initial diagnostic split between schizophrenia spectrum and affective disorder had a good (> 80 %) Positive Predictive Validity and Sensitivity. The main diagnostic shift was an influx to schizophrenia spectrum disorder (n = 6). These patients... (More)
- The purpose was to examine the long-term stability of a diagnosis of psychotic disorder in adolescence and to focus on diagnostic change over time. A total of 88 patients with a first episode of early onset psychosis (before 19 years) were followed up an average of 10.5 years (range 5.1-18.2) after admission. This report includes the 68 patients who could be traced and interviewed with the Positive and Negative Symptom Scale and lifetime Structured Clinical Interview for DSM-IV diagnosis. An initial diagnostic split between schizophrenia spectrum and affective disorder had a good (> 80 %) Positive Predictive Validity and Sensitivity. The main diagnostic shift was an influx to schizophrenia spectrum disorder (n = 6). These patients resembled the stable affective group (n = 27) in premorbid and prodromal aspects but changed over time to resemble the poor outcome of the stable schizophrenia spectrum group (n = 28) albeit with fewer negative symptoms and a better social function. Family history of nonaffective psychosis in first or second degree relatives was often found in the "change to schizophrenia group". A diagnosis in adolescence of schizophrenia spectrum or affective psychotic disorder is usually stable over time. A subgroup of non-schizophrenia patients go on to develop a schizophrenia spectrum disorder. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1126630
- author
- Jarbin, Håkan LU and von Knorring, Anne-Liis
- organization
- publishing date
- 2003
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- bipolar disorder, diagnosis, affective disorder, schizophrenia, adolescence
- in
- European Child & Adolescent Psychiatry
- volume
- 12
- issue
- 1
- pages
- 15 - 22
- publisher
- Springer
- external identifiers
-
- pmid:12601560
- scopus:0037226661
- pmid:12601560
- ISSN
- 1435-165X
- DOI
- 10.1007/s00787-003-0300-z
- language
- English
- LU publication?
- yes
- id
- 7b295a6f-3a61-435b-8105-4167eafcba3c (old id 1126630)
- date added to LUP
- 2016-04-01 16:07:13
- date last changed
- 2022-01-28 17:28:08
@article{7b295a6f-3a61-435b-8105-4167eafcba3c,
abstract = {{The purpose was to examine the long-term stability of a diagnosis of psychotic disorder in adolescence and to focus on diagnostic change over time. A total of 88 patients with a first episode of early onset psychosis (before 19 years) were followed up an average of 10.5 years (range 5.1-18.2) after admission. This report includes the 68 patients who could be traced and interviewed with the Positive and Negative Symptom Scale and lifetime Structured Clinical Interview for DSM-IV diagnosis. An initial diagnostic split between schizophrenia spectrum and affective disorder had a good (> 80 %) Positive Predictive Validity and Sensitivity. The main diagnostic shift was an influx to schizophrenia spectrum disorder (n = 6). These patients resembled the stable affective group (n = 27) in premorbid and prodromal aspects but changed over time to resemble the poor outcome of the stable schizophrenia spectrum group (n = 28) albeit with fewer negative symptoms and a better social function. Family history of nonaffective psychosis in first or second degree relatives was often found in the "change to schizophrenia group". A diagnosis in adolescence of schizophrenia spectrum or affective psychotic disorder is usually stable over time. A subgroup of non-schizophrenia patients go on to develop a schizophrenia spectrum disorder.}},
author = {{Jarbin, Håkan and von Knorring, Anne-Liis}},
issn = {{1435-165X}},
keywords = {{bipolar disorder; diagnosis; affective disorder; schizophrenia; adolescence}},
language = {{eng}},
number = {{1}},
pages = {{15--22}},
publisher = {{Springer}},
series = {{European Child & Adolescent Psychiatry}},
title = {{Diagnostic stability in adolescent onset psychotic disorders}},
url = {{http://dx.doi.org/10.1007/s00787-003-0300-z}},
doi = {{10.1007/s00787-003-0300-z}},
volume = {{12}},
year = {{2003}},
}