Boronic Acid Modified Polymer Nanoparticles for Enhanced Bacterial Deactivation
(2019) In ChemBioChem 20(24). p.2991-2995- Abstract
- A new method has been developed to enhance the antibacterial efficiency of traditional antibiotics. Chloramphenicol‐imprinted polymer particles were decorated with boronic acid to improve their binding to both Gram‐negative and ‐positive bacteria. The polymer particles have a high antibiotic loading and provide a slow release of the antibiotic payload to deactivate the target bacteria. The boronic acid modified polymer particles not only contribute to enhanced antibacterial efficiency, but also have the potential to act as scavengers to remove unused antibiotic from the environment.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/7b89dd42-2361-4499-a269-68fdbb215ae2
- author
- Gong, Haiyue LU ; Liu, Weifeng ; Carlquist, Magnus LU and Ye, Lei LU
- organization
- publishing date
- 2019
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- antibiotics, drug delivery, molecular imprinting, polymers, template synthesis
- in
- ChemBioChem
- volume
- 20
- issue
- 24
- pages
- 5 pages
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- pmid:31243881
- scopus:85074373084
- ISSN
- 1439-4227
- DOI
- 10.1002/cbic.201900406
- language
- English
- LU publication?
- yes
- id
- 7b89dd42-2361-4499-a269-68fdbb215ae2
- date added to LUP
- 2020-08-09 11:52:30
- date last changed
- 2022-04-03 04:11:12
@article{7b89dd42-2361-4499-a269-68fdbb215ae2, abstract = {{A new method has been developed to enhance the antibacterial efficiency of traditional antibiotics. Chloramphenicol‐imprinted polymer particles were decorated with boronic acid to improve their binding to both Gram‐negative and ‐positive bacteria. The polymer particles have a high antibiotic loading and provide a slow release of the antibiotic payload to deactivate the target bacteria. The boronic acid modified polymer particles not only contribute to enhanced antibacterial efficiency, but also have the potential to act as scavengers to remove unused antibiotic from the environment.}}, author = {{Gong, Haiyue and Liu, Weifeng and Carlquist, Magnus and Ye, Lei}}, issn = {{1439-4227}}, keywords = {{antibiotics; drug delivery; molecular imprinting; polymers; template synthesis}}, language = {{eng}}, number = {{24}}, pages = {{2991--2995}}, publisher = {{John Wiley & Sons Inc.}}, series = {{ChemBioChem}}, title = {{Boronic Acid Modified Polymer Nanoparticles for Enhanced Bacterial Deactivation}}, url = {{http://dx.doi.org/10.1002/cbic.201900406}}, doi = {{10.1002/cbic.201900406}}, volume = {{20}}, year = {{2019}}, }