Circulating particles during cardiac surgery.
(2009) In Interactive Cardiovascular and Thoracic Surgery- Abstract
- Shed blood is known to be a source of lipid micro-emboli in cardiac surgery. The aim of this study was to characterize the occurrence of these particles at different stages of the operation, and to study their occurrence in the circulation at multiple time-points after the retransfusion of shed blood. 44 patients undergoing routine surgery with cardiopulmonary bypass were included. Blood was sampled from the surgical field at different sampling locations during the operation. Shed blood was collected in a transfusion bag and retransfused. After which, blood was sampled from the arterial line of the heart-lung machine. A Coulter counter was used for particle determinion. The mean volume of shed blood collected was 340+/-215 ml. Particles in... (More)
- Shed blood is known to be a source of lipid micro-emboli in cardiac surgery. The aim of this study was to characterize the occurrence of these particles at different stages of the operation, and to study their occurrence in the circulation at multiple time-points after the retransfusion of shed blood. 44 patients undergoing routine surgery with cardiopulmonary bypass were included. Blood was sampled from the surgical field at different sampling locations during the operation. Shed blood was collected in a transfusion bag and retransfused. After which, blood was sampled from the arterial line of the heart-lung machine. A Coulter counter was used for particle determinion. The mean volume of shed blood collected was 340+/-215 ml. Particles in the size range 10-60 microm were found at varying concentrations, with the highest concentrations being found in blood collected after cannulation and from the pleura. After retransfusion of this blood, a biphasic response was seen in the blood drawn from the efferent line of the heart-lung machine. Particles are found in shed blood at all times during cardiac surgery, and when this blood was retransfused an increase was seen in particle concentration in the heart-lung machine. Keywords: Particles; Lipid particles; Circulation; Shed mediastinal blood. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1302696
- author
- Bjursten, Henrik LU ; Eyjolfsson, Atli LU ; Scicluna, Sara LU ; Paulsson, Per LU and Johnsson, Per
- organization
- publishing date
- 2009-02-10
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Interactive Cardiovascular and Thoracic Surgery
- publisher
- European Association of Cardio-Thoracic Surgery
- external identifiers
-
- pmid:19208660
- scopus:65949084234
- ISSN
- 1569-9285
- DOI
- 10.1510/icvts.2008.187021
- language
- English
- LU publication?
- yes
- id
- 7bddfd7c-b53f-4247-9fa0-862d99f8ef6c (old id 1302696)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/19208660?dopt=Abstract
- date added to LUP
- 2016-04-04 08:41:30
- date last changed
- 2022-01-29 03:53:40
@article{7bddfd7c-b53f-4247-9fa0-862d99f8ef6c,
abstract = {{Shed blood is known to be a source of lipid micro-emboli in cardiac surgery. The aim of this study was to characterize the occurrence of these particles at different stages of the operation, and to study their occurrence in the circulation at multiple time-points after the retransfusion of shed blood. 44 patients undergoing routine surgery with cardiopulmonary bypass were included. Blood was sampled from the surgical field at different sampling locations during the operation. Shed blood was collected in a transfusion bag and retransfused. After which, blood was sampled from the arterial line of the heart-lung machine. A Coulter counter was used for particle determinion. The mean volume of shed blood collected was 340+/-215 ml. Particles in the size range 10-60 microm were found at varying concentrations, with the highest concentrations being found in blood collected after cannulation and from the pleura. After retransfusion of this blood, a biphasic response was seen in the blood drawn from the efferent line of the heart-lung machine. Particles are found in shed blood at all times during cardiac surgery, and when this blood was retransfused an increase was seen in particle concentration in the heart-lung machine. Keywords: Particles; Lipid particles; Circulation; Shed mediastinal blood.}},
author = {{Bjursten, Henrik and Eyjolfsson, Atli and Scicluna, Sara and Paulsson, Per and Johnsson, Per}},
issn = {{1569-9285}},
language = {{eng}},
month = {{02}},
publisher = {{European Association of Cardio-Thoracic Surgery}},
series = {{Interactive Cardiovascular and Thoracic Surgery}},
title = {{Circulating particles during cardiac surgery.}},
url = {{http://dx.doi.org/10.1510/icvts.2008.187021}},
doi = {{10.1510/icvts.2008.187021}},
year = {{2009}},
}