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Sleep duration and risk of cancer incidence and mortality : A pooled analysis of six population-based cohorts in Japan

Wilunda, Calistus ; Abe, Sarah Krull ; Svensson, Thomas LU ; Sawada, Norie ; Tsugane, Shoichiro ; Wada, Keiko ; Nagata, Chisato ; Kimura, Takashi ; Tamakoshi, Akiko and Sugawara, Yumi , et al. (2022) In International Journal of Cancer 151(7). p.1068-1080
Abstract

Sleep duration is emerging as an important modifiable risk factor for morbidity and mortality. We assessed the association between sleep duration and cancer incidence and mortality among Japanese adults using data from six population-based cohorts with 271 694 participants. During a total follow-up period of about 5.9 million person-years, we identified 40 751 incident cancer cases and 18 323 cancer deaths. We computed study-specific hazard ratios (HRs) and 95% confidence intervals (CIs) using Cox proportional hazards regression models and pooled the estimates using random-effects meta-analysis. Sleep duration of ≥10 hours (vs 7 hours) was associated with increased risk of cancer incidence among women (HR 1.19, 95% CI 1.02-1.38), but... (More)

Sleep duration is emerging as an important modifiable risk factor for morbidity and mortality. We assessed the association between sleep duration and cancer incidence and mortality among Japanese adults using data from six population-based cohorts with 271 694 participants. During a total follow-up period of about 5.9 million person-years, we identified 40 751 incident cancer cases and 18 323 cancer deaths. We computed study-specific hazard ratios (HRs) and 95% confidence intervals (CIs) using Cox proportional hazards regression models and pooled the estimates using random-effects meta-analysis. Sleep duration of ≥10 hours (vs 7 hours) was associated with increased risk of cancer incidence among women (HR 1.19, 95% CI 1.02-1.38), but not men, and increased risk of cancer mortality among men (HR 1.18, 95% CI 1.00-1.39) and women (HR 1.44, 95% CI 1.20-1.73). Sleep duration of ≤5 hours (vs 7 hours) was not associated with cancer incidence and mortality. However, among postmenopausal women, sleep durations of both ≤5 and ≥10 hours (vs 7 hours) were associated with an increased risk of cancer mortality. Among Japanese adults, sleep duration of ≥10 hours is associated with increased risk of cancer incidence and mortality among women and cancer mortality among men.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
International Journal of Cancer
volume
151
issue
7
pages
1068 - 1080
publisher
John Wiley & Sons Inc.
external identifiers
  • pmid:35616624
  • scopus:85131504956
ISSN
0020-7136
DOI
10.1002/ijc.34133
language
English
LU publication?
yes
additional info
© 2022 UICC.
id
7c0ca369-d854-4594-b008-01d79fcb9450
date added to LUP
2022-06-09 11:18:58
date last changed
2024-06-27 14:53:25
@article{7c0ca369-d854-4594-b008-01d79fcb9450,
  abstract     = {{<p>Sleep duration is emerging as an important modifiable risk factor for morbidity and mortality. We assessed the association between sleep duration and cancer incidence and mortality among Japanese adults using data from six population-based cohorts with 271 694 participants. During a total follow-up period of about 5.9 million person-years, we identified 40 751 incident cancer cases and 18 323 cancer deaths. We computed study-specific hazard ratios (HRs) and 95% confidence intervals (CIs) using Cox proportional hazards regression models and pooled the estimates using random-effects meta-analysis. Sleep duration of ≥10 hours (vs 7 hours) was associated with increased risk of cancer incidence among women (HR 1.19, 95% CI 1.02-1.38), but not men, and increased risk of cancer mortality among men (HR 1.18, 95% CI 1.00-1.39) and women (HR 1.44, 95% CI 1.20-1.73). Sleep duration of ≤5 hours (vs 7 hours) was not associated with cancer incidence and mortality. However, among postmenopausal women, sleep durations of both ≤5 and ≥10 hours (vs 7 hours) were associated with an increased risk of cancer mortality. Among Japanese adults, sleep duration of ≥10 hours is associated with increased risk of cancer incidence and mortality among women and cancer mortality among men.</p>}},
  author       = {{Wilunda, Calistus and Abe, Sarah Krull and Svensson, Thomas and Sawada, Norie and Tsugane, Shoichiro and Wada, Keiko and Nagata, Chisato and Kimura, Takashi and Tamakoshi, Akiko and Sugawara, Yumi and Tsuji, Ichiro and Ito, Hidemi and Kitamura, Tetsuhisa and Sakata, Ritsu and Mizoue, Tetsuya and Matsuo, Keitaro and Tanaka, Keitaro and Lin, Yingsong and Inoue, Manami}},
  issn         = {{0020-7136}},
  language     = {{eng}},
  number       = {{7}},
  pages        = {{1068--1080}},
  publisher    = {{John Wiley & Sons Inc.}},
  series       = {{International Journal of Cancer}},
  title        = {{Sleep duration and risk of cancer incidence and mortality : A pooled analysis of six population-based cohorts in Japan}},
  url          = {{http://dx.doi.org/10.1002/ijc.34133}},
  doi          = {{10.1002/ijc.34133}},
  volume       = {{151}},
  year         = {{2022}},
}