Horizontal gene transfer: a critical view
(2003) In Proceedings of the National Academy of Sciences 100(17). p.9658-9662- Abstract
- It has been suggested that horizontal gene transfer (HGT) is the "essence of phylogeny." In contrast, much data suggest that this is an exaggeration resulting in part from a reliance on inadequate methods to identify HGT events. In addition, the assumption that HGT is a ubiquitous influence throughout evolution is questionable. Instead, rampant global HGT is likely to have been relevant only to primitive genomes. In modern organisms we suggest that both the range and frequencies of HGT are constrained most often by selective barriers. As a consequence those HGT events that do occur most often have little influence on genome phylogeny. Although HGT does occur with important evolutionary consequences, classical Darwinian lineages seem to be... (More)
- It has been suggested that horizontal gene transfer (HGT) is the "essence of phylogeny." In contrast, much data suggest that this is an exaggeration resulting in part from a reliance on inadequate methods to identify HGT events. In addition, the assumption that HGT is a ubiquitous influence throughout evolution is questionable. Instead, rampant global HGT is likely to have been relevant only to primitive genomes. In modern organisms we suggest that both the range and frequencies of HGT are constrained most often by selective barriers. As a consequence those HGT events that do occur most often have little influence on genome phylogeny. Although HGT does occur with important evolutionary consequences, classical Darwinian lineages seem to be the dominant mode of evolution for modern organisms. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/945082
- author
- Kurland, Charles LU ; Canbäck, Björn LU and Berg, Otto
- organization
- publishing date
- 2003
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Proceedings of the National Academy of Sciences
- volume
- 100
- issue
- 17
- pages
- 9658 - 9662
- publisher
- National Academy of Sciences
- external identifiers
-
- scopus:0042191905
- pmid:12902542
- ISSN
- 1091-6490
- DOI
- 10.1073/pnas.1632870100
- language
- English
- LU publication?
- yes
- id
- 7c775ad7-d44e-4e98-8939-f0d2b5591b04 (old id 945082)
- date added to LUP
- 2016-04-01 11:58:17
- date last changed
- 2022-01-26 20:55:05
@article{7c775ad7-d44e-4e98-8939-f0d2b5591b04,
abstract = {{It has been suggested that horizontal gene transfer (HGT) is the "essence of phylogeny." In contrast, much data suggest that this is an exaggeration resulting in part from a reliance on inadequate methods to identify HGT events. In addition, the assumption that HGT is a ubiquitous influence throughout evolution is questionable. Instead, rampant global HGT is likely to have been relevant only to primitive genomes. In modern organisms we suggest that both the range and frequencies of HGT are constrained most often by selective barriers. As a consequence those HGT events that do occur most often have little influence on genome phylogeny. Although HGT does occur with important evolutionary consequences, classical Darwinian lineages seem to be the dominant mode of evolution for modern organisms.}},
author = {{Kurland, Charles and Canbäck, Björn and Berg, Otto}},
issn = {{1091-6490}},
language = {{eng}},
number = {{17}},
pages = {{9658--9662}},
publisher = {{National Academy of Sciences}},
series = {{Proceedings of the National Academy of Sciences}},
title = {{Horizontal gene transfer: a critical view}},
url = {{http://dx.doi.org/10.1073/pnas.1632870100}},
doi = {{10.1073/pnas.1632870100}},
volume = {{100}},
year = {{2003}},
}