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Technical recommendations for implementation of Volumetric Modulated Arc Therapy and Helical Tomotherapy Total Body Irradiation

Seravalli, Enrica ; Bosman, Mirjam E ; Han, Chunhui ; Losert, Christoph ; Pazos, Montserrat ; Engström, Per E LU ; Engellau, Jacob LU ; Fulcheri, Christian P L ; Zucchetti, Claudio and Saldi, Simonetta , et al. (2024) In Radiotherapy and Oncology 197.
Abstract

As a component of myeloablative conditioning before allogeneic hematopoietic stem cell transplantation (HSCT), Total Body Irradiation (TBI) is employed in radiotherapy centers all over the world. In recent and coming years, many centers are changing their technical setup from a conventional TBI technique to multi-isocenter conformal arc therapy techniques such as Volumetric Modulated Arc Therapy (VMAT) or Helical Tomotherapy (HT). These techniques allow better homogeneity and control of the target prescription dose, and provide more freedom for individualized organ-at-risk sparing. The technical design of multi-isocenter/multi-plan conformal TBI is complex and should be developed carefully. A group of early adopters with conformal TBI... (More)

As a component of myeloablative conditioning before allogeneic hematopoietic stem cell transplantation (HSCT), Total Body Irradiation (TBI) is employed in radiotherapy centers all over the world. In recent and coming years, many centers are changing their technical setup from a conventional TBI technique to multi-isocenter conformal arc therapy techniques such as Volumetric Modulated Arc Therapy (VMAT) or Helical Tomotherapy (HT). These techniques allow better homogeneity and control of the target prescription dose, and provide more freedom for individualized organ-at-risk sparing. The technical design of multi-isocenter/multi-plan conformal TBI is complex and should be developed carefully. A group of early adopters with conformal TBI experience using different treatment machines and treatment planning systems came together to develop technical recommendations and share experiences, in order to assist departments wishing to implement conformal TBI, and to provide ideas for standardization of practices.

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publishing date
type
Contribution to journal
publication status
published
subject
keywords
Humans, Radiotherapy, Intensity-Modulated/methods, Whole-Body Irradiation/methods, Radiotherapy Planning, Computer-Assisted/methods, Radiotherapy Dosage, Hematopoietic Stem Cell Transplantation/methods, Organs at Risk/radiation effects
in
Radiotherapy and Oncology
volume
197
article number
110366
publisher
Elsevier
external identifiers
  • pmid:38830537
  • scopus:85195410827
ISSN
1879-0887
DOI
10.1016/j.radonc.2024.110366
language
English
LU publication?
no
additional info
Copyright © 2024 The Author(s). Published by Elsevier B.V. All rights reserved.
id
7c8a6da7-a1a2-4bfb-a23a-4092086f5709
date added to LUP
2025-01-02 14:22:50
date last changed
2025-07-04 19:54:27
@article{7c8a6da7-a1a2-4bfb-a23a-4092086f5709,
  abstract     = {{<p>As a component of myeloablative conditioning before allogeneic hematopoietic stem cell transplantation (HSCT), Total Body Irradiation (TBI) is employed in radiotherapy centers all over the world. In recent and coming years, many centers are changing their technical setup from a conventional TBI technique to multi-isocenter conformal arc therapy techniques such as Volumetric Modulated Arc Therapy (VMAT) or Helical Tomotherapy (HT). These techniques allow better homogeneity and control of the target prescription dose, and provide more freedom for individualized organ-at-risk sparing. The technical design of multi-isocenter/multi-plan conformal TBI is complex and should be developed carefully. A group of early adopters with conformal TBI experience using different treatment machines and treatment planning systems came together to develop technical recommendations and share experiences, in order to assist departments wishing to implement conformal TBI, and to provide ideas for standardization of practices.</p>}},
  author       = {{Seravalli, Enrica and Bosman, Mirjam E and Han, Chunhui and Losert, Christoph and Pazos, Montserrat and Engström, Per E and Engellau, Jacob and Fulcheri, Christian P L and Zucchetti, Claudio and Saldi, Simonetta and Ferrer, Carlos and Ocanto, Abrahams and Hiniker, Susan M and Clark, Catharine H and Hussein, Mohammad and Misson-Yates, Sarah and Kobyzeva, Daria A and Loginova, Anna A and Hoeben, Bianca A W}},
  issn         = {{1879-0887}},
  keywords     = {{Humans; Radiotherapy, Intensity-Modulated/methods; Whole-Body Irradiation/methods; Radiotherapy Planning, Computer-Assisted/methods; Radiotherapy Dosage; Hematopoietic Stem Cell Transplantation/methods; Organs at Risk/radiation effects}},
  language     = {{eng}},
  publisher    = {{Elsevier}},
  series       = {{Radiotherapy and Oncology}},
  title        = {{Technical recommendations for implementation of Volumetric Modulated Arc Therapy and Helical Tomotherapy Total Body Irradiation}},
  url          = {{http://dx.doi.org/10.1016/j.radonc.2024.110366}},
  doi          = {{10.1016/j.radonc.2024.110366}},
  volume       = {{197}},
  year         = {{2024}},
}