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Malignant dysphagia : Palliation with esophageal stents - Long-term results in 100 patients

Cwikiel, Wojciech LU ; Tranberg, Karl Göran LU ; Cwikiel, Magdalena LU and Lillo-Gil, Ramon (1998) In Radiology 207(2). p.513-518
Abstract

PURPOSE: To evaluate the long-term palliative effect of self-expanding nitinol esophagael stents in patients with malignant dysphagia. MATERIALS AND METHODS: One hundred patients with severe dysphagia secondary to malignant esophageal strictures were treated with self-expanding nitinol stents. The strictures were caused by squamous carcinoma (n = 43), adenocarcinoma (n = 28), anastomotic tumor recurrence (n = 14), and mediastinal tumor (n = 15). RESULTS: One hundred six stents were successfully positioned in 100 patients. Attempts to insert a second, coaxial stent were unsuccessfully in two patients; a second stent was placed incorrectly in another patient. Statistically significant (P < .001) reduction of dysphagia was noted after... (More)

PURPOSE: To evaluate the long-term palliative effect of self-expanding nitinol esophagael stents in patients with malignant dysphagia. MATERIALS AND METHODS: One hundred patients with severe dysphagia secondary to malignant esophageal strictures were treated with self-expanding nitinol stents. The strictures were caused by squamous carcinoma (n = 43), adenocarcinoma (n = 28), anastomotic tumor recurrence (n = 14), and mediastinal tumor (n = 15). RESULTS: One hundred six stents were successfully positioned in 100 patients. Attempts to insert a second, coaxial stent were unsuccessfully in two patients; a second stent was placed incorrectly in another patient. Statistically significant (P < .001) reduction of dysphagia was noted after expansion of the stents. Complications consisted of incomplete expansion secondary to stent twisting (n = 4), stent, migration (n = 4), tumor ingrowth (n = 17), tumor overgrowth (n = 3), food impaction (n = 5), fracture of stent wires (n = 2), benign strictures at stent edges (n = 2), tumor bleeding (n = 3), and esophagorespiratory fistula (n = 5). The primary patency rate was 75% (77 of 102 stents); the secondary patency rate was 94% (96 of 102 stents). The survival time (mean, 6.2 months; range, 0.1-47 months) varied with the diagnosis. CONCLUSION: Placement of self-expanding nitinol stents is safe and has a good long-term palliative effect on dysphagia in patients with malignant esophageal strictures.

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author
; ; and
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Esophagus, grafts and prostheses, Esophagus, interventional procedure, Esophagus, neoplasms, Esophagus, stenosis or obstruction, Stents and prostheses
in
Radiology
volume
207
issue
2
pages
513 - 518
publisher
Radiological Society of North America
external identifiers
  • scopus:0031807627
  • pmid:9577503
ISSN
0033-8419
DOI
10.1148/radiology.207.2.9577503
language
English
LU publication?
no
id
7cd5b74d-d887-44aa-9552-281abb57c265
date added to LUP
2019-06-15 16:53:29
date last changed
2024-08-06 22:03:33
@article{7cd5b74d-d887-44aa-9552-281abb57c265,
  abstract     = {{<p>PURPOSE: To evaluate the long-term palliative effect of self-expanding nitinol esophagael stents in patients with malignant dysphagia. MATERIALS AND METHODS: One hundred patients with severe dysphagia secondary to malignant esophageal strictures were treated with self-expanding nitinol stents. The strictures were caused by squamous carcinoma (n = 43), adenocarcinoma (n = 28), anastomotic tumor recurrence (n = 14), and mediastinal tumor (n = 15). RESULTS: One hundred six stents were successfully positioned in 100 patients. Attempts to insert a second, coaxial stent were unsuccessfully in two patients; a second stent was placed incorrectly in another patient. Statistically significant (P &lt; .001) reduction of dysphagia was noted after expansion of the stents. Complications consisted of incomplete expansion secondary to stent twisting (n = 4), stent, migration (n = 4), tumor ingrowth (n = 17), tumor overgrowth (n = 3), food impaction (n = 5), fracture of stent wires (n = 2), benign strictures at stent edges (n = 2), tumor bleeding (n = 3), and esophagorespiratory fistula (n = 5). The primary patency rate was 75% (77 of 102 stents); the secondary patency rate was 94% (96 of 102 stents). The survival time (mean, 6.2 months; range, 0.1-47 months) varied with the diagnosis. CONCLUSION: Placement of self-expanding nitinol stents is safe and has a good long-term palliative effect on dysphagia in patients with malignant esophageal strictures.</p>}},
  author       = {{Cwikiel, Wojciech and Tranberg, Karl Göran and Cwikiel, Magdalena and Lillo-Gil, Ramon}},
  issn         = {{0033-8419}},
  keywords     = {{Esophagus, grafts and prostheses; Esophagus, interventional procedure; Esophagus, neoplasms; Esophagus, stenosis or obstruction; Stents and prostheses}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{513--518}},
  publisher    = {{Radiological Society of North America}},
  series       = {{Radiology}},
  title        = {{Malignant dysphagia : Palliation with esophageal stents - Long-term results in 100 patients}},
  url          = {{http://dx.doi.org/10.1148/radiology.207.2.9577503}},
  doi          = {{10.1148/radiology.207.2.9577503}},
  volume       = {{207}},
  year         = {{1998}},
}