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Prevalence and incidence of diabetes mellitus : a nationwide population-based pharmaco-epidemiological study in Sweden

Jansson, S P O ; Fall, K ; Brus, O ; Magnuson, A ; Wändell, P LU ; Östgren, C J LU and Rolandsson, O (2015) In Diabetic Medicine: A journal of the British Diabetic Association 32(10). p.28-1319
Abstract

AIM: To investigate the changes in prevalence and incidence of pharmacologically and non-pharmacologically treated diabetes in Sweden during 2005 to 2013.

METHODS: We obtained data on gender, date of birth and pharmacologically and non-pharmacologically treated diabetes from national registers for all Swedish residents.

RESULTS: During the study period a total of 240 871 new cases of pharmacologically treated diabetes was found. The age-standardized incidence during the follow-up was 4.34 and 3.16 per 1000 individuals in men and women, respectively. A decreasing time trend in incidence for men of 0.6% per year (0.994, 95% CI 0.989-0.999) and for women of 0.7% per year (0.993, 95% CI 0.986-0.999) was observed. The... (More)

AIM: To investigate the changes in prevalence and incidence of pharmacologically and non-pharmacologically treated diabetes in Sweden during 2005 to 2013.

METHODS: We obtained data on gender, date of birth and pharmacologically and non-pharmacologically treated diabetes from national registers for all Swedish residents.

RESULTS: During the study period a total of 240 871 new cases of pharmacologically treated diabetes was found. The age-standardized incidence during the follow-up was 4.34 and 3.16 per 1000 individuals in men and women, respectively. A decreasing time trend in incidence for men of 0.6% per year (0.994, 95% CI 0.989-0.999) and for women of 0.7% per year (0.993, 95% CI 0.986-0.999) was observed. The age-standardized prevalence increased from 41.9 and 29.9 per 1000 in 2005/2006 to 50.8 and 34.6 in 2012/2013 in men and women, respectively. This corresponds to an annually increasing time trend for both men (1.024, 95% CI 1.022-1.027) and women (1.019, 95% CI 1.016-1.021). The total age-standardized prevalence of pharmacologically and non-pharmacologically treated diabetes (2012) was 46.9 per 1000 (55.6 for men and 38.8 for women). This corresponds to an annually increasing time trend (2010-2012) for both men (1.017, 95% CI 1.013-1.021) and women (1.012, 95% CI 1.008-1.016).

CONCLUSIONS: The prevalence of pharmacologically treated diabetes increased moderately during 8 years of follow-up, while the incidence decreased modestly. This is in contrast to the results reported by most other studies. The total prevalence of diabetes (both pharmacologically and non-pharmacologically treated) in Sweden is relatively low, from a global viewpoint.

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publishing date
type
Contribution to journal
publication status
published
subject
keywords
Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Diabetes Mellitus/drug therapy, Female, Humans, Hypoglycemic Agents/therapeutic use, Incidence, Infant, Infant, Newborn, Male, Middle Aged, Pharmacoepidemiology, Prevalence, Sweden/epidemiology, Young Adult
in
Diabetic Medicine: A journal of the British Diabetic Association
volume
32
issue
10
pages
28 - 1319
publisher
Wiley-Blackwell
external identifiers
  • scopus:84941941016
  • pmid:25662570
ISSN
1464-5491
DOI
10.1111/dme.12716
project
Nationwide research collaboration in family medicine and type 2 diabetes - Swedish Primary Care Diabetes (SPACE)
language
English
LU publication?
no
additional info
© 2015 The Authors. Diabetic Medicine © 2015 Diabetes UK.
id
7e70ba6f-c840-4491-8b41-4d556a909896
date added to LUP
2024-02-09 16:55:52
date last changed
2024-02-10 04:07:34
@article{7e70ba6f-c840-4491-8b41-4d556a909896,
  abstract     = {{<p>AIM: To investigate the changes in prevalence and incidence of pharmacologically and non-pharmacologically treated diabetes in Sweden during 2005 to 2013.</p><p>METHODS: We obtained data on gender, date of birth and pharmacologically and non-pharmacologically treated diabetes from national registers for all Swedish residents.</p><p>RESULTS: During the study period a total of 240 871 new cases of pharmacologically treated diabetes was found. The age-standardized incidence during the follow-up was 4.34 and 3.16 per 1000 individuals in men and women, respectively. A decreasing time trend in incidence for men of 0.6% per year (0.994, 95% CI 0.989-0.999) and for women of 0.7% per year (0.993, 95% CI 0.986-0.999) was observed. The age-standardized prevalence increased from 41.9 and 29.9 per 1000 in 2005/2006 to 50.8 and 34.6 in 2012/2013 in men and women, respectively. This corresponds to an annually increasing time trend for both men (1.024, 95% CI 1.022-1.027) and women (1.019, 95% CI 1.016-1.021). The total age-standardized prevalence of pharmacologically and non-pharmacologically treated diabetes (2012) was 46.9 per 1000 (55.6 for men and 38.8 for women). This corresponds to an annually increasing time trend (2010-2012) for both men (1.017, 95% CI 1.013-1.021) and women (1.012, 95% CI 1.008-1.016).</p><p>CONCLUSIONS: The prevalence of pharmacologically treated diabetes increased moderately during 8 years of follow-up, while the incidence decreased modestly. This is in contrast to the results reported by most other studies. The total prevalence of diabetes (both pharmacologically and non-pharmacologically treated) in Sweden is relatively low, from a global viewpoint.</p>}},
  author       = {{Jansson, S P O and Fall, K and Brus, O and Magnuson, A and Wändell, P and Östgren, C J and Rolandsson, O}},
  issn         = {{1464-5491}},
  keywords     = {{Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Diabetes Mellitus/drug therapy; Female; Humans; Hypoglycemic Agents/therapeutic use; Incidence; Infant; Infant, Newborn; Male; Middle Aged; Pharmacoepidemiology; Prevalence; Sweden/epidemiology; Young Adult}},
  language     = {{eng}},
  number       = {{10}},
  pages        = {{28--1319}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Diabetic Medicine: A journal of the British Diabetic Association}},
  title        = {{Prevalence and incidence of diabetes mellitus : a nationwide population-based pharmaco-epidemiological study in Sweden}},
  url          = {{http://dx.doi.org/10.1111/dme.12716}},
  doi          = {{10.1111/dme.12716}},
  volume       = {{32}},
  year         = {{2015}},
}