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Risk factors for erysipelas and cellulitis: A national cohort study

Jansåker, Filip LU orcid ; Li, Xinjun LU ; Stenberg, Henning LU ; Sundquist, Kristina LU and Forsberg, Per-Ola LU (2026) In Next Research 5. p.1-7
Abstract
Objectives Examining risk factors for erysipelas and cellulitis in adults using national registers and primary healthcare data. Methods A nationwide open cohort study including 7580,645 Swedish men and women (2001–2018) was conducted. The outcomes were erysipelas and cellulitis (skin infections). The predictors were sociodemographic factors (sex, age, education- and family income levels, region of residency and country of origin), family history of skin infections, and comorbidities—alcoholism, chronic respiratory disease, diabetes, and obesity. Cox regression models were used to estimate hazard ratios (HRs) and 95 % confidence intervals (CIs). Results Familial association of erysipelas (HR 1.28; 95 % CI, 1.26–1.30) and cellulitis (1.23;... (More)
Objectives Examining risk factors for erysipelas and cellulitis in adults using national registers and primary healthcare data. Methods A nationwide open cohort study including 7580,645 Swedish men and women (2001–2018) was conducted. The outcomes were erysipelas and cellulitis (skin infections). The predictors were sociodemographic factors (sex, age, education- and family income levels, region of residency and country of origin), family history of skin infections, and comorbidities—alcoholism, chronic respiratory disease, diabetes, and obesity. Cox regression models were used to estimate hazard ratios (HRs) and 95 % confidence intervals (CIs). Results Familial association of erysipelas (HR 1.28; 95 % CI, 1.26–1.30) and cellulitis (1.23; 1.20–1.25) were observed. Several sociodemographic factors were associated with erysipelas and cellulitis. Men had higher risk of erysipelas (1.16; 1.15–1.17) but lower cellulitis risk (0.95; 0.94–0.96) compared to women. Comorbidities were associated with erysipelas and cellulitis, e.g., diabetes mellitus was associated with HRs of 2.00 (1.97–2.02) for erysipelas and 2.23 (2.19–2.27) for cellulitis. Conclusion This nationwide study identified familial and sociodemographic associations of erysipelas and cellulitis. Alcoholism, chronic respiratory disease, diabetes mellitus, and obesity were associated with erysipelas and cellulitis. (Less)
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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Cellulitis, Diabetes mellitus, Erysipelas, Familial association, Sociodemographic factors
in
Next Research
volume
5
article number
101279
pages
1 - 7
ISSN
3050-4759
DOI
10.1016/j.nexres.2025.101279
language
English
LU publication?
yes
id
7ef3d480-4a95-4feb-bae7-4e2a0ea81d57
date added to LUP
2026-08-24 08:54:15
date last changed
2026-08-24 09:23:48
@article{7ef3d480-4a95-4feb-bae7-4e2a0ea81d57,
  abstract     = {{Objectives Examining risk factors for erysipelas and cellulitis in adults using national registers and primary healthcare data. Methods A nationwide open cohort study including 7580,645 Swedish men and women (2001–2018) was conducted. The outcomes were erysipelas and cellulitis (skin infections). The predictors were sociodemographic factors (sex, age, education- and family income levels, region of residency and country of origin), family history of skin infections, and comorbidities—alcoholism, chronic respiratory disease, diabetes, and obesity. Cox regression models were used to estimate hazard ratios (HRs) and 95 % confidence intervals (CIs). Results Familial association of erysipelas (HR 1.28; 95 % CI, 1.26–1.30) and cellulitis (1.23; 1.20–1.25) were observed. Several sociodemographic factors were associated with erysipelas and cellulitis. Men had higher risk of erysipelas (1.16; 1.15–1.17) but lower cellulitis risk (0.95; 0.94–0.96) compared to women. Comorbidities were associated with erysipelas and cellulitis, e.g., diabetes mellitus was associated with HRs of 2.00 (1.97–2.02) for erysipelas and 2.23 (2.19–2.27) for cellulitis. Conclusion This nationwide study identified familial and sociodemographic associations of erysipelas and cellulitis. Alcoholism, chronic respiratory disease, diabetes mellitus, and obesity were associated with erysipelas and cellulitis.}},
  author       = {{Jansåker, Filip and Li, Xinjun and Stenberg, Henning and Sundquist, Kristina and Forsberg, Per-Ola}},
  issn         = {{3050-4759}},
  keywords     = {{Cellulitis; Diabetes mellitus; Erysipelas; Familial association; Sociodemographic factors}},
  language     = {{eng}},
  pages        = {{1--7}},
  series       = {{Next Research}},
  title        = {{Risk factors for erysipelas and cellulitis: A national cohort study}},
  url          = {{http://dx.doi.org/10.1016/j.nexres.2025.101279}},
  doi          = {{10.1016/j.nexres.2025.101279}},
  volume       = {{5}},
  year         = {{2026}},
}