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Induced mutations in circadian clock regulator Mat-a facilitated short-season adaptation and range extension in cultivated barley

Zakhrabekova, Shakhira LU ; Gough, S. P.; Braumann, I.; Muller, A. H.; Lundqvist, J.; Ahmann, K.; Dockter, C.; Matyszczak, I.; Kurowska, M. and Druka, A., et al. (2012) In Proceedings of the National Academy of Sciences 109(11). p.4326-4331
Abstract
Time to flowering has an important impact on yield and has been a key trait in the domestication of crop plants and the spread of agriculture. In 1961, the cultivar Mari (mat-a.8) was the very first induced early barley (Hordeum vulgare L.) mutant to be released into commercial production. Mari extended the range of two-row spring barley cultivation as a result of its photoperiod insensitivity. Since its release, Mari or its derivatives have been used extensively across the world to facilitate short-season adaptation and further geographic range extension. By exploiting an extended historical collection of early-flowering mutants of barley, we identified Praematurum-a (Mat-a), the gene responsible for this key adaptive phenotype, as a... (More)
Time to flowering has an important impact on yield and has been a key trait in the domestication of crop plants and the spread of agriculture. In 1961, the cultivar Mari (mat-a.8) was the very first induced early barley (Hordeum vulgare L.) mutant to be released into commercial production. Mari extended the range of two-row spring barley cultivation as a result of its photoperiod insensitivity. Since its release, Mari or its derivatives have been used extensively across the world to facilitate short-season adaptation and further geographic range extension. By exploiting an extended historical collection of early-flowering mutants of barley, we identified Praematurum-a (Mat-a), the gene responsible for this key adaptive phenotype, as a homolog of the Arabidopsis thaliana circadian clock regulator Early Flowering 3 (Elf3). We characterized 87 induced mat-a mutant lines and identified >20 different mat-a alleles that had clear mutations leading to a defective putative ELF3 protein. Expression analysis of HvElf3 and Gigantea in mutant and wild-type plants demonstrated that mat-a mutations disturb the flowering pathway, leading to the early phenotype. Alleles of Mat-a therefore have important and demonstrated breeding value in barley but probably also in many other day-length-sensitive crop plants, where they may tune adaptation to different geographic regions and climatic conditions, a critical issue in times of global warming. (Less)
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keywords
Hordeum/*genetics/*growth & development/physiology, Genetic Linkage, Genetic Association Studies, Plant/*genetics, Genes, Plant, Gene Expression Regulation, Gene Expression Profiling, Flowers/genetics, Plant/genetics, DNA, Circadian Clocks/*genetics, Physiological/*genetics, Adaptation, Agriculture, Molecular Sequence Data, Mutation/*genetics, Phenotype, Physical Chromosome Mapping, Plant Proteins/genetics/metabolism, *Seasons, Sequence Analysis, Synteny/genetics
in
Proceedings of the National Academy of Sciences
volume
109
issue
11
pages
4326 - 4331
publisher
National Acad Sciences
external identifiers
  • scopus:84858173210
ISSN
1091-6490
DOI
10.1073/pnas.1113009109
language
English
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no
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e9f31289-f36e-4ed9-aeaa-309ea1141429 (old id 8001640)
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2015-09-29 10:00:15
date last changed
2017-10-29 03:22:52
@article{e9f31289-f36e-4ed9-aeaa-309ea1141429,
  abstract     = {Time to flowering has an important impact on yield and has been a key trait in the domestication of crop plants and the spread of agriculture. In 1961, the cultivar Mari (mat-a.8) was the very first induced early barley (Hordeum vulgare L.) mutant to be released into commercial production. Mari extended the range of two-row spring barley cultivation as a result of its photoperiod insensitivity. Since its release, Mari or its derivatives have been used extensively across the world to facilitate short-season adaptation and further geographic range extension. By exploiting an extended historical collection of early-flowering mutants of barley, we identified Praematurum-a (Mat-a), the gene responsible for this key adaptive phenotype, as a homolog of the Arabidopsis thaliana circadian clock regulator Early Flowering 3 (Elf3). We characterized 87 induced mat-a mutant lines and identified >20 different mat-a alleles that had clear mutations leading to a defective putative ELF3 protein. Expression analysis of HvElf3 and Gigantea in mutant and wild-type plants demonstrated that mat-a mutations disturb the flowering pathway, leading to the early phenotype. Alleles of Mat-a therefore have important and demonstrated breeding value in barley but probably also in many other day-length-sensitive crop plants, where they may tune adaptation to different geographic regions and climatic conditions, a critical issue in times of global warming.},
  author       = {Zakhrabekova, Shakhira and Gough, S. P. and Braumann, I. and Muller, A. H. and Lundqvist, J. and Ahmann, K. and Dockter, C. and Matyszczak, I. and Kurowska, M. and Druka, A. and Waugh, R. and Graner, A. and Stein, N. and Steuernagel, B. and Lundqvist, U. and Hansson, Mats},
  issn         = {1091-6490},
  keyword      = {Hordeum/*genetics/*growth & development/physiology,Genetic Linkage,Genetic Association Studies,Plant/*genetics,Genes,Plant,Gene Expression Regulation,Gene Expression Profiling,Flowers/genetics,Plant/genetics,DNA,Circadian Clocks/*genetics,Physiological/*genetics,Adaptation,Agriculture,Molecular Sequence Data,Mutation/*genetics,Phenotype,Physical Chromosome Mapping,Plant Proteins/genetics/metabolism,*Seasons,Sequence Analysis,Synteny/genetics},
  language     = {eng},
  number       = {11},
  pages        = {4326--4331},
  publisher    = {National Acad Sciences},
  series       = {Proceedings of the National Academy of Sciences},
  title        = {Induced mutations in circadian clock regulator Mat-a facilitated short-season adaptation and range extension in cultivated barley},
  url          = {http://dx.doi.org/10.1073/pnas.1113009109},
  volume       = {109},
  year         = {2012},
}