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Uncovering Brain Network Modules in Major Depression During Naturalistic Music Perception With Block Term Decomposition

Zhu, Yongjie ; Hao, Yuxing ; Liu, Jia LU and Cong, Fengyu (2025) In IEEE Transactions on Cognitive and Developmental Systems 17(4). p.874-883
Abstract

Major depressive disorder (MDD) has been linked to altered brain networks and might be relieved by music therapy. Yet, the neurophysiological basis, especially the functional network mechanism, of music therapy on depression remains poorly understood. Here, we apply a novel dynamic module detection method based on block term decomposition (BTD) to examine the reorganization of time-varying topological network structures during music listening in MDD using electroencephalography (EEG). Specifically, temporal adjacency matrices generated using a sliding-window technique form a three-way tensor. The multilinear rank-(L,L,1) BTD is applied to directly derive hidden network modules with specific time evolution from the temporally... (More)

Major depressive disorder (MDD) has been linked to altered brain networks and might be relieved by music therapy. Yet, the neurophysiological basis, especially the functional network mechanism, of music therapy on depression remains poorly understood. Here, we apply a novel dynamic module detection method based on block term decomposition (BTD) to examine the reorganization of time-varying topological network structures during music listening in MDD using electroencephalography (EEG). Specifically, temporal adjacency matrices generated using a sliding-window technique form a three-way tensor. The multilinear rank-(L,L,1) BTD is applied to directly derive hidden network modules with specific time evolution from the temporally concatenated tensors for each frequency band. After temporal correlation analysis with musical features extracted from music stimuli, we identify several frequency-dependent network modules with specific temporal patterns modulated by musical features. These modular networks encompass subnetworks of default mode, frontoparietal, language, and sensorimotor networks involved in the delta, alpha, and beta bands, exhibiting significantly different modulations by music between healthy control and MDD groups. These results implicate that the altered oscillatory modular networks might affect the dynamic processing of musical features for MDD patients, which could offer valuable perspectives on revealing the neural mechanisms of music therapy for MDD.

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author
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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Community detection, depression, electroencephalography (EEG), modular network, music listening, music therapy, naturalis tensor decomposition
in
IEEE Transactions on Cognitive and Developmental Systems
volume
17
issue
4
pages
10 pages
publisher
IEEE - Institute of Electrical and Electronics Engineers Inc.
external identifiers
  • scopus:85213696829
ISSN
2379-8920
DOI
10.1109/TCDS.2024.3523020
language
English
LU publication?
yes
id
8027c757-7e13-404a-8ade-097bc8d68a0b
date added to LUP
2026-01-12 08:11:33
date last changed
2026-01-12 08:12:50
@article{8027c757-7e13-404a-8ade-097bc8d68a0b,
  abstract     = {{<p>Major depressive disorder (MDD) has been linked to altered brain networks and might be relieved by music therapy. Yet, the neurophysiological basis, especially the functional network mechanism, of music therapy on depression remains poorly understood. Here, we apply a novel dynamic module detection method based on block term decomposition (BTD) to examine the reorganization of time-varying topological network structures during music listening in MDD using electroencephalography (EEG). Specifically, temporal adjacency matrices generated using a sliding-window technique form a three-way tensor. The multilinear rank-(L,L,1) BTD is applied to directly derive hidden network modules with specific time evolution from the temporally concatenated tensors for each frequency band. After temporal correlation analysis with musical features extracted from music stimuli, we identify several frequency-dependent network modules with specific temporal patterns modulated by musical features. These modular networks encompass subnetworks of default mode, frontoparietal, language, and sensorimotor networks involved in the delta, alpha, and beta bands, exhibiting significantly different modulations by music between healthy control and MDD groups. These results implicate that the altered oscillatory modular networks might affect the dynamic processing of musical features for MDD patients, which could offer valuable perspectives on revealing the neural mechanisms of music therapy for MDD.</p>}},
  author       = {{Zhu, Yongjie and Hao, Yuxing and Liu, Jia and Cong, Fengyu}},
  issn         = {{2379-8920}},
  keywords     = {{Community detection; depression; electroencephalography (EEG); modular network; music listening; music therapy; naturalis tensor decomposition}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{874--883}},
  publisher    = {{IEEE - Institute of Electrical and Electronics Engineers Inc.}},
  series       = {{IEEE Transactions on Cognitive and Developmental Systems}},
  title        = {{Uncovering Brain Network Modules in Major Depression During Naturalistic Music Perception With Block Term Decomposition}},
  url          = {{http://dx.doi.org/10.1109/TCDS.2024.3523020}},
  doi          = {{10.1109/TCDS.2024.3523020}},
  volume       = {{17}},
  year         = {{2025}},
}