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Six-week follow-up after HIV-1 exposure: a position statement from the Public Health Agency of Sweden and the Swedish Reference Group for Antiviral Therapy.

Gaines, Hans; Albert, Jan; Axelsson, Maria; Berglund, Torsten; Gisslén, Magnus; Sönnerborg, Anders; Blaxhult, Anders; Bogdanovic, Gordana; Brytting, Maria and Carlander, Christina, et al. (2015) In Infectious Diseases p.1-6
Abstract
In 2014 the Public Health Agency of Sweden and the Swedish Reference Group for Antiviral Therapy (RAV) conducted a review and analysis of the state of knowledge on the duration of follow-up after exposure to human immunodeficiency virus (HIV). Up until then a follow-up of 12 weeks after exposure had been recommended, but improved tests and new information on early diagnosis motivated a re-evaluation of the national recommendations by experts representing infectious diseases and microbiology, county medical officers, the RAV, the Public Health Agency, and other national authorities. Based on the current state of knowledge the Public Health Agency of Sweden and the RAV recommend, starting in April 2015, a follow-up period of 6 weeks after... (More)
In 2014 the Public Health Agency of Sweden and the Swedish Reference Group for Antiviral Therapy (RAV) conducted a review and analysis of the state of knowledge on the duration of follow-up after exposure to human immunodeficiency virus (HIV). Up until then a follow-up of 12 weeks after exposure had been recommended, but improved tests and new information on early diagnosis motivated a re-evaluation of the national recommendations by experts representing infectious diseases and microbiology, county medical officers, the RAV, the Public Health Agency, and other national authorities. Based on the current state of knowledge the Public Health Agency of Sweden and the RAV recommend, starting in April 2015, a follow-up period of 6 weeks after possible HIV-1 exposure, if HIV testing is performed using laboratory-based combination tests detecting both HIV antibody and antigen. If point-of-care rapid HIV tests are used, a follow-up period of 8 weeks is recommended, because currently available rapid tests have insufficient sensitivity for detection of HIV-1 antigen. A follow-up period of 12 weeks is recommended after a possible exposure for HIV-2, since presently used assays do not include HIV-2 antigens and only limited information is available on the development of HIV antibodies during early HIV-2 infection. If pre- or post-exposure prophylaxis is administered, the follow-up period is recommended to begin after completion of prophylaxis. Even if infection cannot be reliably excluded before the end of the recommended follow-up period, HIV testing should be performed at first contact for persons who seek such testing. (Less)
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Infectious Diseases
issue
sep 28
pages
1 - 6
publisher
Taylor & Francis
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  • pmid:26414596
  • wos:000371986500001
  • scopus:84962296605
ISSN
2374-4243
DOI
10.3109/23744235.2015.1089593
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English
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yes
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52522da9-80a4-4fdf-936a-5de599dada06 (old id 8034666)
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http://www.ncbi.nlm.nih.gov/pubmed/26414596?dopt=Abstract
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2015-10-03 13:10:28
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2017-08-08 09:20:45
@article{52522da9-80a4-4fdf-936a-5de599dada06,
  abstract     = {In 2014 the Public Health Agency of Sweden and the Swedish Reference Group for Antiviral Therapy (RAV) conducted a review and analysis of the state of knowledge on the duration of follow-up after exposure to human immunodeficiency virus (HIV). Up until then a follow-up of 12 weeks after exposure had been recommended, but improved tests and new information on early diagnosis motivated a re-evaluation of the national recommendations by experts representing infectious diseases and microbiology, county medical officers, the RAV, the Public Health Agency, and other national authorities. Based on the current state of knowledge the Public Health Agency of Sweden and the RAV recommend, starting in April 2015, a follow-up period of 6 weeks after possible HIV-1 exposure, if HIV testing is performed using laboratory-based combination tests detecting both HIV antibody and antigen. If point-of-care rapid HIV tests are used, a follow-up period of 8 weeks is recommended, because currently available rapid tests have insufficient sensitivity for detection of HIV-1 antigen. A follow-up period of 12 weeks is recommended after a possible exposure for HIV-2, since presently used assays do not include HIV-2 antigens and only limited information is available on the development of HIV antibodies during early HIV-2 infection. If pre- or post-exposure prophylaxis is administered, the follow-up period is recommended to begin after completion of prophylaxis. Even if infection cannot be reliably excluded before the end of the recommended follow-up period, HIV testing should be performed at first contact for persons who seek such testing.},
  author       = {Gaines, Hans and Albert, Jan and Axelsson, Maria and Berglund, Torsten and Gisslén, Magnus and Sönnerborg, Anders and Blaxhult, Anders and Bogdanovic, Gordana and Brytting, Maria and Carlander, Christina and Flamholc, Leo and Follin, Per and Haggar, Axana and Hagstam, Per and Johansson, Marcus and Navér, Lars and Persson Blom, Jenny and Samuelson, Agneta and Ström, Helena and Sundqvist, Martin and Svedhem Johansson, Veronica and Tegmark Wisell, Karin and Tegnell, Anders and Thorstensson, Rigmor},
  issn         = {2374-4243},
  language     = {eng},
  number       = {sep 28},
  pages        = {1--6},
  publisher    = {Taylor & Francis},
  series       = {Infectious Diseases},
  title        = {Six-week follow-up after HIV-1 exposure: a position statement from the Public Health Agency of Sweden and the Swedish Reference Group for Antiviral Therapy.},
  url          = {http://dx.doi.org/10.3109/23744235.2015.1089593},
  year         = {2015},
}