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Novel flow cytometry technique for detection of Plasmodium falciparum specific B-cells in humans: increased levels of specific B-cells in ongoing infection.

Lugaajju, Allan; Reddy, Sreenivasulu B; Rönnberg, Caroline; Wahlgren, Mats; Kironde, Fred and Persson, Kristina LU (2015) In Malaria Journal 14(1).
Abstract
Malaria caused by Plasmodium falciparum is still a major health threat in endemic areas especially for children below 5 years of age. While it is recognized that antibody immunity plays an important role in controlling the disease, knowledge of the mechanisms of sustenance and natural boosting of immunity is very limited. Before, it has not been possible to investigate malaria specific B-cells directly in flow cytometry, making it difficult to know how much of a B cell response is due to malaria, or how much is due to other immunological stimulators.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Malaria Journal
volume
14
issue
1
publisher
BioMed Central
external identifiers
  • pmid:26410225
  • wos:000361787000002
  • scopus:84942421994
ISSN
1475-2875
DOI
10.1186/s12936-015-0911-0
language
English
LU publication?
yes
id
505090ca-904b-4b2c-9016-e26089c938fb (old id 8034857)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26410225?dopt=Abstract
date added to LUP
2015-10-03 13:41:05
date last changed
2017-11-12 03:39:43
@article{505090ca-904b-4b2c-9016-e26089c938fb,
  abstract     = {Malaria caused by Plasmodium falciparum is still a major health threat in endemic areas especially for children below 5 years of age. While it is recognized that antibody immunity plays an important role in controlling the disease, knowledge of the mechanisms of sustenance and natural boosting of immunity is very limited. Before, it has not been possible to investigate malaria specific B-cells directly in flow cytometry, making it difficult to know how much of a B cell response is due to malaria, or how much is due to other immunological stimulators.},
  articleno    = {370},
  author       = {Lugaajju, Allan and Reddy, Sreenivasulu B and Rönnberg, Caroline and Wahlgren, Mats and Kironde, Fred and Persson, Kristina},
  issn         = {1475-2875},
  language     = {eng},
  number       = {1},
  publisher    = {BioMed Central},
  series       = {Malaria Journal},
  title        = {Novel flow cytometry technique for detection of Plasmodium falciparum specific B-cells in humans: increased levels of specific B-cells in ongoing infection.},
  url          = {http://dx.doi.org/10.1186/s12936-015-0911-0},
  volume       = {14},
  year         = {2015},
}