Novel flow cytometry technique for detection of Plasmodium falciparum specific B-cells in humans: increased levels of specific B-cells in ongoing infection.
(2015) In Malaria Journal 14(1).- Abstract
- Malaria caused by Plasmodium falciparum is still a major health threat in endemic areas especially for children below 5 years of age. While it is recognized that antibody immunity plays an important role in controlling the disease, knowledge of the mechanisms of sustenance and natural boosting of immunity is very limited. Before, it has not been possible to investigate malaria specific B-cells directly in flow cytometry, making it difficult to know how much of a B cell response is due to malaria, or how much is due to other immunological stimulators.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8034857
- author
- Lugaajju, Allan ; Reddy, Sreenivasulu B ; Rönnberg, Caroline ; Wahlgren, Mats ; Kironde, Fred and Persson, Kristina LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Malaria Journal
- volume
- 14
- issue
- 1
- article number
- 370
- publisher
- BioMed Central (BMC)
- external identifiers
-
- pmid:26410225
- wos:000361787000002
- scopus:84942421994
- pmid:26410225
- ISSN
- 1475-2875
- DOI
- 10.1186/s12936-015-0911-0
- language
- English
- LU publication?
- yes
- id
- 505090ca-904b-4b2c-9016-e26089c938fb (old id 8034857)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26410225?dopt=Abstract
- date added to LUP
- 2016-04-01 13:41:57
- date last changed
- 2024-04-16 09:11:33
@article{505090ca-904b-4b2c-9016-e26089c938fb, abstract = {{Malaria caused by Plasmodium falciparum is still a major health threat in endemic areas especially for children below 5 years of age. While it is recognized that antibody immunity plays an important role in controlling the disease, knowledge of the mechanisms of sustenance and natural boosting of immunity is very limited. Before, it has not been possible to investigate malaria specific B-cells directly in flow cytometry, making it difficult to know how much of a B cell response is due to malaria, or how much is due to other immunological stimulators.}}, author = {{Lugaajju, Allan and Reddy, Sreenivasulu B and Rönnberg, Caroline and Wahlgren, Mats and Kironde, Fred and Persson, Kristina}}, issn = {{1475-2875}}, language = {{eng}}, number = {{1}}, publisher = {{BioMed Central (BMC)}}, series = {{Malaria Journal}}, title = {{Novel flow cytometry technique for detection of Plasmodium falciparum specific B-cells in humans: increased levels of specific B-cells in ongoing infection.}}, url = {{http://dx.doi.org/10.1186/s12936-015-0911-0}}, doi = {{10.1186/s12936-015-0911-0}}, volume = {{14}}, year = {{2015}}, }