Hepatocyte growth factor in cerebrospinal fluid differentiates community-acquired or nosocomial septic meningitis from other causes of pleocytosis.
(2015) In Fluids and Barriers of the CNS 12(1). p.22-22- Abstract
- Due to anatomical restrictions, the inflammatory response to intracerebral bacterial infections exposes swollen brain tissues to pressure and ischemia, resulting in life-threatening damage. Rapid diagnosis and immediate empirical antibiotic therapy is highly important. However, diagnosing meningitis in patients after neurosurgery is complicated, due to brain tissue damage and changes in cerebrospinal fluid (CSF) caused by surgery. Hepatocyte growth factor (HGF) is a local, acute-phase protein with healing properties. Previous studies on community-acquired septic meningitis reported high levels of intrathecally produced HGF. The present study focused on nosocomial meningitis in assessing the levels of HGF in the CSF.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8034917
- author
- Ramezani, Amir ; Nägga, Katarina LU ; Hansson, Oskar LU ; Lönn, Johanna ; Sjöwall, Johanna ; Katoozian, Fateme ; Mansouri, Sepahdar and Nayeri, Fariba
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Fluids and Barriers of the CNS
- volume
- 12
- issue
- 1
- pages
- 22 - 22
- publisher
- BioMed Central (BMC)
- external identifiers
-
- pmid:26408034
- scopus:84942246778
- pmid:26408034
- wos:000210116300001
- ISSN
- 2045-8118
- DOI
- 10.1186/s12987-015-0020-z
- language
- English
- LU publication?
- yes
- id
- 88f4f52d-b335-4ec7-967d-315b029f9d30 (old id 8034917)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26408034?dopt=Abstract
- date added to LUP
- 2016-04-04 09:09:12
- date last changed
- 2022-03-15 17:59:15
@article{88f4f52d-b335-4ec7-967d-315b029f9d30, abstract = {{Due to anatomical restrictions, the inflammatory response to intracerebral bacterial infections exposes swollen brain tissues to pressure and ischemia, resulting in life-threatening damage. Rapid diagnosis and immediate empirical antibiotic therapy is highly important. However, diagnosing meningitis in patients after neurosurgery is complicated, due to brain tissue damage and changes in cerebrospinal fluid (CSF) caused by surgery. Hepatocyte growth factor (HGF) is a local, acute-phase protein with healing properties. Previous studies on community-acquired septic meningitis reported high levels of intrathecally produced HGF. The present study focused on nosocomial meningitis in assessing the levels of HGF in the CSF.}}, author = {{Ramezani, Amir and Nägga, Katarina and Hansson, Oskar and Lönn, Johanna and Sjöwall, Johanna and Katoozian, Fateme and Mansouri, Sepahdar and Nayeri, Fariba}}, issn = {{2045-8118}}, language = {{eng}}, number = {{1}}, pages = {{22--22}}, publisher = {{BioMed Central (BMC)}}, series = {{Fluids and Barriers of the CNS}}, title = {{Hepatocyte growth factor in cerebrospinal fluid differentiates community-acquired or nosocomial septic meningitis from other causes of pleocytosis.}}, url = {{http://dx.doi.org/10.1186/s12987-015-0020-z}}, doi = {{10.1186/s12987-015-0020-z}}, volume = {{12}}, year = {{2015}}, }