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Meningococcal Serogroup B Bivalent rLP2086 Vaccine Elicits Broad and Robust Serum Bactericidal Responses in Healthy Adolescents.

Vesikari, Timo; Østergaard, Lars; Diez-Domingo, Javier; Wysocki, Jacek; Flodmark, Carl-Erik LU ; Beeslaar, Johannes; Eiden, Joseph; Jiang, Qin; Jansen, Kathrin U and Jones, Thomas R, et al. (2016) In Journal of the Pediatric Infectious Diseases Society
Abstract
Neisseria meningitidis serogroup B (MnB) is a leading cause of invasive meningococcal disease in adolescents and young adults. A recombinant factor H binding protein (fHBP) vaccine (Trumenba(®); bivalent rLP2086) was recently approved in the United States in individuals aged 10-25 years. Immunogenicity and safety of 2- or 3-dose schedules of bivalent rLP2086 were assessed in adolescents.
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Journal of the Pediatric Infectious Diseases Society
publisher
Oxford University Press
external identifiers
  • pmid:26407272
  • scopus:85006216378
ISSN
2048-7207
DOI
10.1093/jpids/piv039
language
English
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yes
id
be2438c4-9272-4cfa-9ba3-9e59b4092bed (old id 8034955)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26407272?dopt=Abstract
date added to LUP
2015-10-03 15:51:47
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2017-04-09 04:34:16
@article{be2438c4-9272-4cfa-9ba3-9e59b4092bed,
  abstract     = {Neisseria meningitidis serogroup B (MnB) is a leading cause of invasive meningococcal disease in adolescents and young adults. A recombinant factor H binding protein (fHBP) vaccine (Trumenba(®); bivalent rLP2086) was recently approved in the United States in individuals aged 10-25 years. Immunogenicity and safety of 2- or 3-dose schedules of bivalent rLP2086 were assessed in adolescents.},
  author       = {Vesikari, Timo and Østergaard, Lars and Diez-Domingo, Javier and Wysocki, Jacek and Flodmark, Carl-Erik and Beeslaar, Johannes and Eiden, Joseph and Jiang, Qin and Jansen, Kathrin U and Jones, Thomas R and Harris, Shannon L and O'Neill, Robert E and York, Laura J and Crowther, Graham and Perez, John L},
  issn         = {2048-7207},
  language     = {eng},
  publisher    = {Oxford University Press},
  series       = {Journal of the Pediatric Infectious Diseases Society},
  title        = {Meningococcal Serogroup B Bivalent rLP2086 Vaccine Elicits Broad and Robust Serum Bactericidal Responses in Healthy Adolescents.},
  url          = {http://dx.doi.org/10.1093/jpids/piv039},
  year         = {2016},
}