Risk prediction by genetic risk scores for coronary heart disease is independent of self-reported family history.
Tada, Hayato ; Melander, Olle LU
; Louie, Judy Z
; Catanese, Joseph J
; Rowland, Charles M
; Devlin, James J
; Kathiresan, Sekar
and Shiffman, Dov
(2015)
In European Heart Journal
- Abstract
- Genetic risk scores (GRSs) have been associated with coronary heart disease (CHD) in large studies. We asked whether expanding an established 27-variant GRS (GRS27) to a 50-variant GRS (GRS50) improved CHD prediction and whether GRSs are independent of self-reported family history of CHD.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8035423
- author
- Tada, Hayato
; Melander, Olle
LU
; Louie, Judy Z
; Catanese, Joseph J
; Rowland, Charles M
; Devlin, James J
; Kathiresan, Sekar
and Shiffman, Dov
- organization
- publishing date
- 2015-09-20
- type
- Contribution to journal
- publication status
- published
- subject
- in
- European Heart Journal
- publisher
- Oxford University Press
- external identifiers
-
- pmid:26392438
- wos:000371250400012
- scopus:84962173287
- pmid:26392438
- ISSN
- 1522-9645
- DOI
- 10.1093/eurheartj/ehv462
- language
- English
- LU publication?
- yes
- id
- 0a361e7e-7b52-4392-a1fe-0cc3478cf29d (old id 8035423)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26392438?dopt=Abstract
- date added to LUP
- 2016-04-04 09:19:21
- date last changed
- 2024-01-12 10:33:47
@article{0a361e7e-7b52-4392-a1fe-0cc3478cf29d,
abstract = {{Genetic risk scores (GRSs) have been associated with coronary heart disease (CHD) in large studies. We asked whether expanding an established 27-variant GRS (GRS27) to a 50-variant GRS (GRS50) improved CHD prediction and whether GRSs are independent of self-reported family history of CHD.}},
author = {{Tada, Hayato and Melander, Olle and Louie, Judy Z and Catanese, Joseph J and Rowland, Charles M and Devlin, James J and Kathiresan, Sekar and Shiffman, Dov}},
issn = {{1522-9645}},
language = {{eng}},
month = {{09}},
publisher = {{Oxford University Press}},
series = {{European Heart Journal}},
title = {{Risk prediction by genetic risk scores for coronary heart disease is independent of self-reported family history.}},
url = {{http://dx.doi.org/10.1093/eurheartj/ehv462}},
doi = {{10.1093/eurheartj/ehv462}},
year = {{2015}},
}