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Expression of functional toll like receptor 4 in estrogen receptor/progesterone receptor-negative breast cancer.

Mehmeti, Meliha LU ; Allaoui, Roni LU ; Bergenfelz, Caroline LU ; Saal, Lao LU ; Ethier, Stephen P; Johansson, Martin LU ; Jirström, Karin LU and Leandersson, Karin LU (2015) In Breast Cancer Research 17(1).
Abstract
Toll-like receptors (TLRs) are a family of pattern recognition receptors that are expressed on cells of the innate immune system. The ligands can be pathogen derived (pathogen associated molecular patterns; PAMPs) or endogenous (damage associated molecular patters; DAMPs) that when bound induces activation of nuclear factor kappa B (NF-κB) and transcription of pro-inflammatory genes. TLRs have also been discovered in various malignant cell types, but with unknown function.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Breast Cancer Research
volume
17
issue
1
publisher
BioMed Central
external identifiers
  • pmid:26392082
  • wos:000361588800001
  • scopus:84958940218
ISSN
1465-5411
DOI
10.1186/s13058-015-0640-x
language
English
LU publication?
yes
id
e872915e-e5a2-46f1-9e2d-a997ca3bbdc4 (old id 8035469)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26392082?dopt=Abstract
date added to LUP
2015-10-03 17:41:33
date last changed
2017-10-22 03:26:06
@article{e872915e-e5a2-46f1-9e2d-a997ca3bbdc4,
  abstract     = {Toll-like receptors (TLRs) are a family of pattern recognition receptors that are expressed on cells of the innate immune system. The ligands can be pathogen derived (pathogen associated molecular patterns; PAMPs) or endogenous (damage associated molecular patters; DAMPs) that when bound induces activation of nuclear factor kappa B (NF-κB) and transcription of pro-inflammatory genes. TLRs have also been discovered in various malignant cell types, but with unknown function.},
  articleno    = {130},
  author       = {Mehmeti, Meliha and Allaoui, Roni and Bergenfelz, Caroline and Saal, Lao and Ethier, Stephen P and Johansson, Martin and Jirström, Karin and Leandersson, Karin},
  issn         = {1465-5411},
  language     = {eng},
  number       = {1},
  publisher    = {BioMed Central},
  series       = {Breast Cancer Research},
  title        = {Expression of functional toll like receptor 4 in estrogen receptor/progesterone receptor-negative breast cancer.},
  url          = {http://dx.doi.org/10.1186/s13058-015-0640-x},
  volume       = {17},
  year         = {2015},
}