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Coronary artery bypass grafting-related bleeding complications in patients treated with ticagrelor or clopidogrel: a nationwide study.

Hansson, Emma C; Jidéus, Lena; Åberg, Bengt; Bjursten, Henrik LU ; Dreifaldt, Mats; Holmgren, Anders; Ivert, Torbjörn; Nozohoor, Shahab; Barbu, Mikael and Svedjeholm, Rolf, et al. (2015) In European Heart Journal
Abstract
Excessive bleeding impairs outcome after coronary artery bypass grafting (CABG). Current guidelines recommend withdrawal of clopidogrel and ticagrelor 5 days (120 h) before elective surgery. Shorter discontinuation would reduce the risk of thrombotic events and save hospital resources, but may increase the risk of bleeding. We investigated whether a shorter discontinuation time before surgery increased the incidence of CABG-related major bleeding complications and compared ticagrelor- and clopidogrel-treated patients.
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European Heart Journal
publisher
Oxford University Press
external identifiers
  • PMID:26330426
  • WOS:000370974300019
  • Scopus:84964614129
ISSN
1522-9645
DOI
10.1093/eurheartj/ehv381
language
English
LU publication?
yes
id
4c426509-f1d4-4983-b7cf-9d81ef756278 (old id 8043475)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26330426?dopt=Abstract
date added to LUP
2015-10-04 19:37:17
date last changed
2017-02-05 04:34:19
@article{4c426509-f1d4-4983-b7cf-9d81ef756278,
  abstract     = {Excessive bleeding impairs outcome after coronary artery bypass grafting (CABG). Current guidelines recommend withdrawal of clopidogrel and ticagrelor 5 days (120 h) before elective surgery. Shorter discontinuation would reduce the risk of thrombotic events and save hospital resources, but may increase the risk of bleeding. We investigated whether a shorter discontinuation time before surgery increased the incidence of CABG-related major bleeding complications and compared ticagrelor- and clopidogrel-treated patients.},
  author       = {Hansson, Emma C and Jidéus, Lena and Åberg, Bengt and Bjursten, Henrik and Dreifaldt, Mats and Holmgren, Anders and Ivert, Torbjörn and Nozohoor, Shahab and Barbu, Mikael and Svedjeholm, Rolf and Jeppsson, Anders},
  issn         = {1522-9645},
  language     = {eng},
  month        = {09},
  publisher    = {Oxford University Press},
  series       = {European Heart Journal},
  title        = {Coronary artery bypass grafting-related bleeding complications in patients treated with ticagrelor or clopidogrel: a nationwide study.},
  url          = {http://dx.doi.org/10.1093/eurheartj/ehv381},
  year         = {2015},
}