Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Ultrasound, hepatic lymph nodes and primary biliary cirrhosis

Lyttkens, Kerstin LU ; Prytz, Hanne LU ; Forsberg, Lillemor ; Hederström, Esbjörn and Hägerstrand, Inga (1992) In Journal of Hepatology 15(1-2). p.136-139
Abstract

Thirty-five consecutive patients with primary biliary cirrhosis were examined using liver biopsy, laboratory tests and ultrasonography of the hepato-duodenal ligament to investigate the possible correlation between enlarged lymph nodes in the hepato-duodenal ligament and biochemical activity, histologic activity or stage and/or humoral immunoreactivity. We found a positive correlation between the size of the largest lymph node and laboratory values of cholestasis, hepatocellular damage and increased humoral immunoreactivity. On the other hand, we found a negative association between lymph node size and hepatocellular function. When twelve of the patients were reexamined after at least 10 months, in the majority of the patients changes... (More)

Thirty-five consecutive patients with primary biliary cirrhosis were examined using liver biopsy, laboratory tests and ultrasonography of the hepato-duodenal ligament to investigate the possible correlation between enlarged lymph nodes in the hepato-duodenal ligament and biochemical activity, histologic activity or stage and/or humoral immunoreactivity. We found a positive correlation between the size of the largest lymph node and laboratory values of cholestasis, hepatocellular damage and increased humoral immunoreactivity. On the other hand, we found a negative association between lymph node size and hepatocellular function. When twelve of the patients were reexamined after at least 10 months, in the majority of the patients changes in lymph node size were accompanied by similar changes in markers of cholestasis, hepatocellular damage and immunoreactivity. Prognostic index was also directly associated with lymph node size in most of these patients. No association between lymph node size and histologic stage was observed.

(Less)
Please use this url to cite or link to this publication:
author
; ; ; and
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Hepatology
volume
15
issue
1-2
pages
4 pages
publisher
Elsevier
external identifiers
  • scopus:0026684473
  • pmid:1506630
ISSN
0168-8278
DOI
10.1016/0168-8278(92)90025-K
language
English
LU publication?
no
id
804aabfb-55f0-44fe-9522-d8e8eeb0468a
date added to LUP
2019-05-28 22:22:27
date last changed
2024-01-01 08:14:24
@article{804aabfb-55f0-44fe-9522-d8e8eeb0468a,
  abstract     = {{<p>Thirty-five consecutive patients with primary biliary cirrhosis were examined using liver biopsy, laboratory tests and ultrasonography of the hepato-duodenal ligament to investigate the possible correlation between enlarged lymph nodes in the hepato-duodenal ligament and biochemical activity, histologic activity or stage and/or humoral immunoreactivity. We found a positive correlation between the size of the largest lymph node and laboratory values of cholestasis, hepatocellular damage and increased humoral immunoreactivity. On the other hand, we found a negative association between lymph node size and hepatocellular function. When twelve of the patients were reexamined after at least 10 months, in the majority of the patients changes in lymph node size were accompanied by similar changes in markers of cholestasis, hepatocellular damage and immunoreactivity. Prognostic index was also directly associated with lymph node size in most of these patients. No association between lymph node size and histologic stage was observed.</p>}},
  author       = {{Lyttkens, Kerstin and Prytz, Hanne and Forsberg, Lillemor and Hederström, Esbjörn and Hägerstrand, Inga}},
  issn         = {{0168-8278}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{1-2}},
  pages        = {{136--139}},
  publisher    = {{Elsevier}},
  series       = {{Journal of Hepatology}},
  title        = {{Ultrasound, hepatic lymph nodes and primary biliary cirrhosis}},
  url          = {{http://dx.doi.org/10.1016/0168-8278(92)90025-K}},
  doi          = {{10.1016/0168-8278(92)90025-K}},
  volume       = {{15}},
  year         = {{1992}},
}