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The bladder trigone : A sensory organ?

Andersson, Karl Erik LU orcid ; Kanai, Anthony and Uvelius, Bengt LU (2026) In Continence 17.
Abstract

The bladder trigone is a distinct anatomical and functional subregion of the urinary bladder, defined by its triangular configuration between the ureteral orifices and the internal urethral orifice. Although traditionally less studied compared to the bladder dome and detrusor body, recent morphological, molecular, and transcriptomic analyses reveal that the trigone is highly specialized. Understanding the trigone's role in sensory signaling, urinary continence, and pathophysiological conditions such as bladder pain syndrome and vesicoureteral reflux provides a basis for developing therapeutic approaches to treat disorders involving this structure.

Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Continence
volume
17
article number
102309
publisher
Elsevier
external identifiers
  • scopus:105027766717
ISSN
2772-9737
DOI
10.1016/j.cont.2025.102309
language
English
LU publication?
yes
id
805a4ab4-ece3-439c-892d-b32913d1fa0c
date added to LUP
2026-02-18 13:36:14
date last changed
2026-02-23 11:28:09
@article{805a4ab4-ece3-439c-892d-b32913d1fa0c,
  abstract     = {{<p>The bladder trigone is a distinct anatomical and functional subregion of the urinary bladder, defined by its triangular configuration between the ureteral orifices and the internal urethral orifice. Although traditionally less studied compared to the bladder dome and detrusor body, recent morphological, molecular, and transcriptomic analyses reveal that the trigone is highly specialized. Understanding the trigone's role in sensory signaling, urinary continence, and pathophysiological conditions such as bladder pain syndrome and vesicoureteral reflux provides a basis for developing therapeutic approaches to treat disorders involving this structure.</p>}},
  author       = {{Andersson, Karl Erik and Kanai, Anthony and Uvelius, Bengt}},
  issn         = {{2772-9737}},
  language     = {{eng}},
  publisher    = {{Elsevier}},
  series       = {{Continence}},
  title        = {{The bladder trigone : A sensory organ?}},
  url          = {{http://dx.doi.org/10.1016/j.cont.2025.102309}},
  doi          = {{10.1016/j.cont.2025.102309}},
  volume       = {{17}},
  year         = {{2026}},
}