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Can a single dose response predict the effect of montelukast on exercise-induced bronchoconstriction?

Kersten, Elin T G ; Akkerman-Nijland, Anne M ; Driessen, Jean M M ; Diamant, Zuzana LU and Thio, Bernard J (2015) In Pediatric Pulmonology
Abstract
Exercise-induced bronchoconstriction (EIB) can be prevented by a single dose of montelukast (MLK). The effect is variable, similar to the variable responsiveness observed after daily treatment with MLK. We hypothesized that the effect of a single MLK-dose (5 or 10 mg) on EIB could predict the clinical effectiveness of longer term once daily treatment.
Please use this url to cite or link to this publication:
author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Pediatric Pulmonology
publisher
John Wiley & Sons Inc.
external identifiers
  • pmid:26492292
  • scopus:84949439526
  • wos:000374303600005
  • pmid:26492292
ISSN
8755-6863
DOI
10.1002/ppul.23324
language
English
LU publication?
yes
id
47dcea73-7cbb-4d63-ac66-98d4ddba84e7 (old id 8148626)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26492292?dopt=Abstract
date added to LUP
2016-04-04 08:30:09
date last changed
2022-03-30 23:39:00
@article{47dcea73-7cbb-4d63-ac66-98d4ddba84e7,
  abstract     = {{Exercise-induced bronchoconstriction (EIB) can be prevented by a single dose of montelukast (MLK). The effect is variable, similar to the variable responsiveness observed after daily treatment with MLK. We hypothesized that the effect of a single MLK-dose (5 or 10 mg) on EIB could predict the clinical effectiveness of longer term once daily treatment.}},
  author       = {{Kersten, Elin T G and Akkerman-Nijland, Anne M and Driessen, Jean M M and Diamant, Zuzana and Thio, Bernard J}},
  issn         = {{8755-6863}},
  language     = {{eng}},
  month        = {{10}},
  publisher    = {{John Wiley & Sons Inc.}},
  series       = {{Pediatric Pulmonology}},
  title        = {{Can a single dose response predict the effect of montelukast on exercise-induced bronchoconstriction?}},
  url          = {{http://dx.doi.org/10.1002/ppul.23324}},
  doi          = {{10.1002/ppul.23324}},
  year         = {{2015}},
}