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Heparin-Binding Protein Measurement Improves the Prediction of Severe Infection With Organ Dysfunction in the Emergency Department.

Linder, Adam LU ; Arnold, Ryan; Boyd, John H; Zindovic, Marko; Zindovic, Igor LU ; Lange, Anna; Paulsson, Magnus LU ; Nyberg, Patrik LU ; Russell, James A and Pritchard, David, et al. (2015) In Critical Care Medicine 43(11). p.2378-2386
Abstract
Early identification of patients with infection and at risk of developing severe disease with organ dysfunction remains a difficult challenge. We aimed to evaluate and validate the heparin-binding protein, a neutrophil-derived mediator of vascular leakage, as a prognostic biomarker for risk of progression to severe sepsis with circulatory failure in a multicenter setting.
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Critical Care Medicine
volume
43
issue
11
pages
2378 - 2386
publisher
Lippincott Williams & Wilkins
external identifiers
  • pmid:26468696
  • wos:000362826200014
  • scopus:84944448352
ISSN
1530-0293
DOI
10.1097/CCM.0000000000001265
language
English
LU publication?
yes
id
aa529a3d-0ddc-45da-b614-03cb3a0b96e7 (old id 8152212)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26468696?dopt=Abstract
date added to LUP
2015-11-03 13:53:59
date last changed
2017-11-05 03:09:30
@article{aa529a3d-0ddc-45da-b614-03cb3a0b96e7,
  abstract     = {Early identification of patients with infection and at risk of developing severe disease with organ dysfunction remains a difficult challenge. We aimed to evaluate and validate the heparin-binding protein, a neutrophil-derived mediator of vascular leakage, as a prognostic biomarker for risk of progression to severe sepsis with circulatory failure in a multicenter setting.},
  author       = {Linder, Adam and Arnold, Ryan and Boyd, John H and Zindovic, Marko and Zindovic, Igor and Lange, Anna and Paulsson, Magnus and Nyberg, Patrik and Russell, James A and Pritchard, David and Christensson, Bertil and Åkesson, Per},
  issn         = {1530-0293},
  language     = {eng},
  number       = {11},
  pages        = {2378--2386},
  publisher    = {Lippincott Williams & Wilkins},
  series       = {Critical Care Medicine},
  title        = {Heparin-Binding Protein Measurement Improves the Prediction of Severe Infection With Organ Dysfunction in the Emergency Department.},
  url          = {http://dx.doi.org/10.1097/CCM.0000000000001265},
  volume       = {43},
  year         = {2015},
}