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Mapping of Perfusion During Full-Thickness Blepharotomy Using Laser Speckle Contrast Imaging

Wiktorin, Anna H C ; Berggren, Johanna V LU orcid ; Malmsjö, Malin LU orcid ; Lindstedt, Sandra LU ; Sheikh, Rafi LU orcid and Bohman, Elin (2022) In Ophthalmic Plastic and Reconstructive Surgery 38(6). p.588-592
Abstract

PURPOSE: The aim of this study was to monitor how the blood perfusion in human upper eyelids is affected during full-thickness blepharotomy.

METHODS: Seven eyelids in 5 patients with upper eyelid retraction due to Graves' disease underwent full-thickness blepharotomy. Perfusion was measured using laser speckle contrast imaging in the eyelid margin and in the conjunctival pedicle.

RESULTS: Immediately following the procedure, a nonsignificant reduction in perfusion was observed in the skin of the pretarsal eyelid margin, being 66% of the initial value (p = n.s.). However, a statistically significant decrease in perfusion, to 53% of the initial value (p < 0.01), was seen in the central pedicle of the conjunctiva. There were... (More)

PURPOSE: The aim of this study was to monitor how the blood perfusion in human upper eyelids is affected during full-thickness blepharotomy.

METHODS: Seven eyelids in 5 patients with upper eyelid retraction due to Graves' disease underwent full-thickness blepharotomy. Perfusion was measured using laser speckle contrast imaging in the eyelid margin and in the conjunctival pedicle.

RESULTS: Immediately following the procedure, a nonsignificant reduction in perfusion was observed in the skin of the pretarsal eyelid margin, being 66% of the initial value (p = n.s.). However, a statistically significant decrease in perfusion, to 53% of the initial value (p < 0.01), was seen in the central pedicle of the conjunctiva. There were no surgical complications such as infection, signs of ischemia, or bleeding.

CONCLUSIONS: In this study, eyelid perfusion was mapped during full-thickness blepharotomy for the first time using laser speckle contrast imaging. The results showed that perfusion is sufficiently preserved during surgery, probably due to the rich vascular supply in the periocular region, which may explain the low risk of postoperative complications such as ischemia and infection.

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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Ophthalmic Plastic and Reconstructive Surgery
volume
38
issue
6
pages
588 - 592
publisher
Lippincott Williams & Wilkins
external identifiers
  • scopus:85141724275
  • pmid:35657677
ISSN
1537-2677
DOI
10.1097/IOP.0000000000002218
language
English
LU publication?
yes
additional info
Copyright © 2022 The American Society of Ophthalmic Plastic and Reconstructive Surgery, Inc.
id
81e2ad7f-c5df-4803-a088-111f2adada39
date added to LUP
2022-06-07 15:28:56
date last changed
2025-03-05 21:25:35
@article{81e2ad7f-c5df-4803-a088-111f2adada39,
  abstract     = {{<p>PURPOSE: The aim of this study was to monitor how the blood perfusion in human upper eyelids is affected during full-thickness blepharotomy.</p><p>METHODS: Seven eyelids in 5 patients with upper eyelid retraction due to Graves' disease underwent full-thickness blepharotomy. Perfusion was measured using laser speckle contrast imaging in the eyelid margin and in the conjunctival pedicle.</p><p>RESULTS: Immediately following the procedure, a nonsignificant reduction in perfusion was observed in the skin of the pretarsal eyelid margin, being 66% of the initial value (p = n.s.). However, a statistically significant decrease in perfusion, to 53% of the initial value (p &lt; 0.01), was seen in the central pedicle of the conjunctiva. There were no surgical complications such as infection, signs of ischemia, or bleeding.</p><p>CONCLUSIONS: In this study, eyelid perfusion was mapped during full-thickness blepharotomy for the first time using laser speckle contrast imaging. The results showed that perfusion is sufficiently preserved during surgery, probably due to the rich vascular supply in the periocular region, which may explain the low risk of postoperative complications such as ischemia and infection.</p>}},
  author       = {{Wiktorin, Anna H C and Berggren, Johanna V and Malmsjö, Malin and Lindstedt, Sandra and Sheikh, Rafi and Bohman, Elin}},
  issn         = {{1537-2677}},
  language     = {{eng}},
  month        = {{06}},
  number       = {{6}},
  pages        = {{588--592}},
  publisher    = {{Lippincott Williams & Wilkins}},
  series       = {{Ophthalmic Plastic and Reconstructive Surgery}},
  title        = {{Mapping of Perfusion During Full-Thickness Blepharotomy Using Laser Speckle Contrast Imaging}},
  url          = {{http://dx.doi.org/10.1097/IOP.0000000000002218}},
  doi          = {{10.1097/IOP.0000000000002218}},
  volume       = {{38}},
  year         = {{2022}},
}