Revisiting the role of the mast cell in asthma.
(2016) In Current Opinion in Pulmonary Medicine 22(1). p.10-17- Abstract
- In humans, mast cells are ubiquitously present in tissues adjacent to external environment and consequently have an important sentential role in host defence, homeostasis and repair. Their key role in allergen-mediated conditions has been recognized for many decades already. So far, therapies targeting mast cells offered clinical efficacy in allergic conditions except for asthma. More recently, sophisticated sampling and detection techniques revealed pleiotrophic immunological and functional properties of mast cells in and beyond asthma with potential clinical and management implications. These findings bring back the mast cell as a key player in the field of asthma and warrant a review of the recent literature.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8235329
- author
- Andersson, Cecilia LU ; Tufvesson, Ellen LU ; Diamant, Zuzana LU and Bjermer, Leif LU
- organization
- publishing date
- 2016
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Current Opinion in Pulmonary Medicine
- volume
- 22
- issue
- 1
- pages
- 10 - 17
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- pmid:26574723
- scopus:84948572836
- wos:000369646600003
- pmid:26574723
- ISSN
- 1531-6971
- DOI
- 10.1097/MCP.0000000000000228
- language
- English
- LU publication?
- yes
- id
- ef9a7012-c185-4216-bb57-c36793931c7a (old id 8235329)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26574723?dopt=Abstract
- date added to LUP
- 2016-04-04 07:55:55
- date last changed
- 2025-04-04 14:31:07
@article{ef9a7012-c185-4216-bb57-c36793931c7a,
abstract = {{In humans, mast cells are ubiquitously present in tissues adjacent to external environment and consequently have an important sentential role in host defence, homeostasis and repair. Their key role in allergen-mediated conditions has been recognized for many decades already. So far, therapies targeting mast cells offered clinical efficacy in allergic conditions except for asthma. More recently, sophisticated sampling and detection techniques revealed pleiotrophic immunological and functional properties of mast cells in and beyond asthma with potential clinical and management implications. These findings bring back the mast cell as a key player in the field of asthma and warrant a review of the recent literature.}},
author = {{Andersson, Cecilia and Tufvesson, Ellen and Diamant, Zuzana and Bjermer, Leif}},
issn = {{1531-6971}},
language = {{eng}},
number = {{1}},
pages = {{10--17}},
publisher = {{Lippincott Williams & Wilkins}},
series = {{Current Opinion in Pulmonary Medicine}},
title = {{Revisiting the role of the mast cell in asthma.}},
url = {{http://dx.doi.org/10.1097/MCP.0000000000000228}},
doi = {{10.1097/MCP.0000000000000228}},
volume = {{22}},
year = {{2016}},
}