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Complications after minor salivary gland biopsy: a retrospective study of 630 patients from two Swedish centres

Olsson, P LU ; Ekblad, F ; Hassler, A ; Bengtsson, Martin LU orcid ; Warfvinge, G ; Mandl, T LU and Kvarnström, M (2023) In Scandinavian Journal of Rheumatology 52(2). p.208-216
Abstract
Objectives
The aims of the study were to investigate the prevalence of impaired sensation after minor salivary gland biopsy (MSGB) in two Swedish centres [Karolinska University Hospital (KUH) and Skåne University Hospital (SUH)] and to assess its impact on quality of life (QoL) and associated risk factors.

Method
A questionnaire including questions regarding the presence of impaired sensation, impact on QoL, and impact on everyday life was sent to patients who had undergone MSGB between 2007 and 2016, and their medical notes were scrutinized.

Results
The study included 630 patients (505 from KUH and 125 from SUH). In KUH the biopsies were performed by rheumatologists and in SUH by dentists or oral and... (More)
Objectives
The aims of the study were to investigate the prevalence of impaired sensation after minor salivary gland biopsy (MSGB) in two Swedish centres [Karolinska University Hospital (KUH) and Skåne University Hospital (SUH)] and to assess its impact on quality of life (QoL) and associated risk factors.

Method
A questionnaire including questions regarding the presence of impaired sensation, impact on QoL, and impact on everyday life was sent to patients who had undergone MSGB between 2007 and 2016, and their medical notes were scrutinized.

Results
The study included 630 patients (505 from KUH and 125 from SUH). In KUH the biopsies were performed by rheumatologists and in SUH by dentists or oral and maxillofacial surgeons (OMSs). Long-standing, probably permanent, impaired sensation after MSGB was reported by 21% of patients, and was associated with lower age and absence of anti-SSA antibodies. Patients with long-standing impaired sensation reported the inconvenience (1–10) of impaired sensation as 4.0 (2.0–7.0) [median (interquartile range)], and 32% reported an influence on their QoL, the reported influence (1–10) on everyday life being 3.0 (1.0–5.0). When comparing the outcomes from KUH and SUH, patients from SUH reported a significantly lower frequency of long-standing impaired sensation (14% vs 23%; p = 0.02).

Conclusion
A high frequency of long-standing impaired sensation after MSGB was found among patients who had undergone MSGB, although it had a low impact on everyday life. The complication frequency was less pronounced when a dentist or an OMS had performed the biopsy. (Less)
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author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Scandinavian Journal of Rheumatology
volume
52
issue
2
pages
208 - 216
publisher
Taylor & Francis
external identifiers
  • scopus:85123413640
  • pmid:35049421
ISSN
1502-7732
DOI
10.1080/03009742.2021.1999671
language
English
LU publication?
yes
id
82b44fb1-b9e9-4a91-b3a5-30c454daa157
date added to LUP
2022-01-20 22:15:42
date last changed
2024-02-29 00:27:31
@article{82b44fb1-b9e9-4a91-b3a5-30c454daa157,
  abstract     = {{Objectives<br/>The aims of the study were to investigate the prevalence of impaired sensation after minor salivary gland biopsy (MSGB) in two Swedish centres [Karolinska University Hospital (KUH) and Skåne University Hospital (SUH)] and to assess its impact on quality of life (QoL) and associated risk factors.<br/><br/>Method<br/>A questionnaire including questions regarding the presence of impaired sensation, impact on QoL, and impact on everyday life was sent to patients who had undergone MSGB between 2007 and 2016, and their medical notes were scrutinized.<br/><br/>Results<br/>The study included 630 patients (505 from KUH and 125 from SUH). In KUH the biopsies were performed by rheumatologists and in SUH by dentists or oral and maxillofacial surgeons (OMSs). Long-standing, probably permanent, impaired sensation after MSGB was reported by 21% of patients, and was associated with lower age and absence of anti-SSA antibodies. Patients with long-standing impaired sensation reported the inconvenience (1–10) of impaired sensation as 4.0 (2.0–7.0) [median (interquartile range)], and 32% reported an influence on their QoL, the reported influence (1–10) on everyday life being 3.0 (1.0–5.0). When comparing the outcomes from KUH and SUH, patients from SUH reported a significantly lower frequency of long-standing impaired sensation (14% vs 23%; p = 0.02).<br/><br/>Conclusion<br/>A high frequency of long-standing impaired sensation after MSGB was found among patients who had undergone MSGB, although it had a low impact on everyday life. The complication frequency was less pronounced when a dentist or an OMS had performed the biopsy.}},
  author       = {{Olsson, P and Ekblad, F and Hassler, A and Bengtsson, Martin and Warfvinge, G and Mandl, T and Kvarnström, M}},
  issn         = {{1502-7732}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{208--216}},
  publisher    = {{Taylor & Francis}},
  series       = {{Scandinavian Journal of Rheumatology}},
  title        = {{Complications after minor salivary gland biopsy: a retrospective study of 630 patients from two Swedish centres}},
  url          = {{http://dx.doi.org/10.1080/03009742.2021.1999671}},
  doi          = {{10.1080/03009742.2021.1999671}},
  volume       = {{52}},
  year         = {{2023}},
}