Optical absorption of blood depends on temperature during a 0.5 ms laser pulse at 586 nm
(1998) In Photochemistry and Photobiology 67(3). p.276-281- Abstract
- Optical properties are important parameters in port wine stain laser treatment models. In this study we investigated whether changes in blood optical properties occur during a 0.5 ms laser pulse, Blood from three volunteers was irradiated in vitro with laser pulses (radiant exposure 2-12 J cm(-2), wavelength 586 nm, pulse length 0.5 ms). Reflection and transmission coefficients, measured using double integrating spheres, decreased slightly during the first part of the pulse. At 2.9 J cm(-2) radiant exposure, the reflectance increased, independent of total radiant exposure of the pulse, This was-caused by blood coagulation, A second sudden increase in reflection and a significant increase in transmission occurred near 6.3 9 cm(-2) and was... (More)
- Optical properties are important parameters in port wine stain laser treatment models. In this study we investigated whether changes in blood optical properties occur during a 0.5 ms laser pulse, Blood from three volunteers was irradiated in vitro with laser pulses (radiant exposure 2-12 J cm(-2), wavelength 586 nm, pulse length 0.5 ms). Reflection and transmission coefficients, measured using double integrating spheres, decreased slightly during the first part of the pulse. At 2.9 J cm(-2) radiant exposure, the reflectance increased, independent of total radiant exposure of the pulse, This was-caused by blood coagulation, A second sudden increase in reflection and a significant increase in transmission occurred near 6.3 9 cm(-2) and was accompanied by a "popping" sound, indicating rapid expansion of bubbles due to blood vaporization. A multilayered model of blood was used to fit calculated transmission coefficient curves to the measurements and determine temperature-dependent optical blood absorption, Heat diffusion was shown to be of minor importance, A 2.5-fold increase in absorption for temperatures increasing from 20 to 100 degrees C, accurately describes transmission coefficients measured up to 2.9 J cm(-2). (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2259653
- author
- Verkruysse, W ; Nilsson, A. M. K ; Milner, T. E ; Beek, J. F ; Lucassen, G. W and van Gemert, M. J. C
- publishing date
- 1998
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Photochemistry and Photobiology
- volume
- 67
- issue
- 3
- pages
- 276 - 281
- publisher
- American Society for Photobiology
- external identifiers
-
- scopus:0032011135
- ISSN
- 0031-8655
- DOI
- 10.1111/j.1751-1097.1998.tb05199.x
- language
- English
- LU publication?
- no
- id
- 82b494a8-af67-40bf-9014-3e4d7b4ca2ab (old id 2259653)
- date added to LUP
- 2016-04-04 07:22:02
- date last changed
- 2022-01-29 02:05:48
@article{82b494a8-af67-40bf-9014-3e4d7b4ca2ab,
abstract = {{Optical properties are important parameters in port wine stain laser treatment models. In this study we investigated whether changes in blood optical properties occur during a 0.5 ms laser pulse, Blood from three volunteers was irradiated in vitro with laser pulses (radiant exposure 2-12 J cm(-2), wavelength 586 nm, pulse length 0.5 ms). Reflection and transmission coefficients, measured using double integrating spheres, decreased slightly during the first part of the pulse. At 2.9 J cm(-2) radiant exposure, the reflectance increased, independent of total radiant exposure of the pulse, This was-caused by blood coagulation, A second sudden increase in reflection and a significant increase in transmission occurred near 6.3 9 cm(-2) and was accompanied by a "popping" sound, indicating rapid expansion of bubbles due to blood vaporization. A multilayered model of blood was used to fit calculated transmission coefficient curves to the measurements and determine temperature-dependent optical blood absorption, Heat diffusion was shown to be of minor importance, A 2.5-fold increase in absorption for temperatures increasing from 20 to 100 degrees C, accurately describes transmission coefficients measured up to 2.9 J cm(-2).}},
author = {{Verkruysse, W and Nilsson, A. M. K and Milner, T. E and Beek, J. F and Lucassen, G. W and van Gemert, M. J. C}},
issn = {{0031-8655}},
language = {{eng}},
number = {{3}},
pages = {{276--281}},
publisher = {{American Society for Photobiology}},
series = {{Photochemistry and Photobiology}},
title = {{Optical absorption of blood depends on temperature during a 0.5 ms laser pulse at 586 nm}},
url = {{https://lup.lub.lu.se/search/files/5135819/2297674.pdf}},
doi = {{10.1111/j.1751-1097.1998.tb05199.x}},
volume = {{67}},
year = {{1998}},
}