Blodkomponenter och helblod – så framställs och används de
(2021) In Läkartidningen 118.- Abstract
Sweden does not have a national blood authority and guidelines for blood transfusions are lacking, leading to varying routines of production and usage of blood in the different regions. The minimum quality requirements are defined in EU Directive 2002/98/EG and in the Swedish SOSFS 2009:28. The standard blood components are red blood cells, plasma and platelets, while special components such as irradiated, washed, frozen-thawed or antigen-matched products are prescribed on certain clinical indications. Thresholds for transfusion of red blood cells and platelets are discussed as well as indications for plasma transfusions. Further, there is evidence that early, balanced blood transfusions in massive bleeding reduce mortality, which has... (More)
Sweden does not have a national blood authority and guidelines for blood transfusions are lacking, leading to varying routines of production and usage of blood in the different regions. The minimum quality requirements are defined in EU Directive 2002/98/EG and in the Swedish SOSFS 2009:28. The standard blood components are red blood cells, plasma and platelets, while special components such as irradiated, washed, frozen-thawed or antigen-matched products are prescribed on certain clinical indications. Thresholds for transfusion of red blood cells and platelets are discussed as well as indications for plasma transfusions. Further, there is evidence that early, balanced blood transfusions in massive bleeding reduce mortality, which has led to requests for blood products in prehospital settings.
(Less)- Abstract (Swedish)
- Krav på innehåll i blodkomponenter, virustest och kvalitetskriterier regleras i ett EU-direktiv och i Socialstyrelsens föreskrifter.
Blodtransfusioner är en vanlig och viktig medicinsk behandling.
Det saknas nationella riktlinjer för transfusionsindikationer och uppföljning av blodtransfusioner i Sverige.
Det finns medicinsk evidens för en generellt restriktiv transfusionsstrategi.
Vid stora blödningar rekommenderas en balanserad ersättning av de olika blodkomponenterna.
Helblod har börjat användas och utvärderas prehospitalt.
- author
- Wikman, Agneta ; Larsson, Stella ; Storry, Jill LU ; Schött, Ulf LU and Sato Folatre, José Gabriel
- alternative title
- Blood components, special components and whole blood - what and to whom?
- publishing date
- 2021-03-15
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Läkartidningen
- volume
- 118
- article number
- 20150
- publisher
- Swedish Medical Association
- external identifiers
-
- scopus:85102915152
- pmid:33720381
- scopus:85102915152
- pmid:33720381
- ISSN
- 0023-7205
- language
- Swedish
- LU publication?
- no
- id
- 8350c904-ce26-483a-8536-83e6dfe7305b
- alternative location
- https://lakartidningen.se/klinik-och-vetenskap-1/artiklar-1/temaartikel/2021/03/blodkomponenter-och-helblod-sa-framstalls-och-anvands-de/
- date added to LUP
- 2021-03-19 19:33:30
- date last changed
- 2024-04-04 01:56:10
@article{8350c904-ce26-483a-8536-83e6dfe7305b,
abstract = {{<p>Sweden does not have a national blood authority and guidelines for blood transfusions are lacking, leading to varying routines of production and usage of blood in the different regions. The minimum quality requirements are defined in EU Directive 2002/98/EG and in the Swedish SOSFS 2009:28. The standard blood components are red blood cells, plasma and platelets, while special components such as irradiated, washed, frozen-thawed or antigen-matched products are prescribed on certain clinical indications. Thresholds for transfusion of red blood cells and platelets are discussed as well as indications for plasma transfusions. Further, there is evidence that early, balanced blood transfusions in massive bleeding reduce mortality, which has led to requests for blood products in prehospital settings.</p>}},
author = {{Wikman, Agneta and Larsson, Stella and Storry, Jill and Schött, Ulf and Sato Folatre, José Gabriel}},
issn = {{0023-7205}},
language = {{swe}},
month = {{03}},
publisher = {{Swedish Medical Association}},
series = {{Läkartidningen}},
title = {{Blodkomponenter och helblod – så framställs och används de}},
url = {{https://lakartidningen.se/klinik-och-vetenskap-1/artiklar-1/temaartikel/2021/03/blodkomponenter-och-helblod-sa-framstalls-och-anvands-de/}},
volume = {{118}},
year = {{2021}},
}