Advanced

HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis.

Bagger, Frederik Otzen; Rapin, Nicolas LU ; Theilgaard-Moench, Kim LU ; Kaczkowski, Bogumil; Thorén, Lina LU ; Jendholm, Johan LU ; Winther, Ole and Porse, Bo T (2013) In Nucleic Acids Research 41(D1). p.1034-1039
Abstract
The HemaExplorer (http://servers.binf.ku.dk/hemaexplorer) is a curated database of processed mRNA Gene expression profiles (GEPs) that provides an easy display of gene expression in haematopoietic cells. HemaExplorer contains GEPs derived from mouse/human haematopoietic stem and progenitor cells as well as from more differentiated cell types. Moreover, data from distinct subtypes of human acute myeloid leukemia is included in the database allowing researchers to directly compare gene expression of leukemic cells with those of their closest normal counterpart. Normalization and batch correction lead to full integrity of the data in the database. The HemaExplorer has comprehensive visualization interface that can make it useful as a daily... (More)
The HemaExplorer (http://servers.binf.ku.dk/hemaexplorer) is a curated database of processed mRNA Gene expression profiles (GEPs) that provides an easy display of gene expression in haematopoietic cells. HemaExplorer contains GEPs derived from mouse/human haematopoietic stem and progenitor cells as well as from more differentiated cell types. Moreover, data from distinct subtypes of human acute myeloid leukemia is included in the database allowing researchers to directly compare gene expression of leukemic cells with those of their closest normal counterpart. Normalization and batch correction lead to full integrity of the data in the database. The HemaExplorer has comprehensive visualization interface that can make it useful as a daily tool for biologists and cancer researchers to assess the expression patterns of genes encountered in research or literature. HemaExplorer is relevant for all research within the fields of leukemia, immunology, cell differentiation and the biology of the haematopoietic system. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Nucleic Acids Research
volume
41
issue
D1
pages
1034 - 1039
publisher
Oxford University Press
external identifiers
  • wos:000312893300147
  • pmid:23143109
  • scopus:84876569352
ISSN
1362-4962
DOI
10.1093/nar/gks1021
language
English
LU publication?
yes
id
84128b36-5544-42a0-8270-9e94ec70bb84 (old id 3219031)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/23143109?dopt=Abstract
date added to LUP
2012-12-17 15:24:26
date last changed
2019-06-02 03:05:43
@article{84128b36-5544-42a0-8270-9e94ec70bb84,
  abstract     = {The HemaExplorer (http://servers.binf.ku.dk/hemaexplorer) is a curated database of processed mRNA Gene expression profiles (GEPs) that provides an easy display of gene expression in haematopoietic cells. HemaExplorer contains GEPs derived from mouse/human haematopoietic stem and progenitor cells as well as from more differentiated cell types. Moreover, data from distinct subtypes of human acute myeloid leukemia is included in the database allowing researchers to directly compare gene expression of leukemic cells with those of their closest normal counterpart. Normalization and batch correction lead to full integrity of the data in the database. The HemaExplorer has comprehensive visualization interface that can make it useful as a daily tool for biologists and cancer researchers to assess the expression patterns of genes encountered in research or literature. HemaExplorer is relevant for all research within the fields of leukemia, immunology, cell differentiation and the biology of the haematopoietic system.},
  author       = {Bagger, Frederik Otzen and Rapin, Nicolas and Theilgaard-Moench, Kim and Kaczkowski, Bogumil and Thorén, Lina and Jendholm, Johan and Winther, Ole and Porse, Bo T},
  issn         = {1362-4962},
  language     = {eng},
  number       = {D1},
  pages        = {1034--1039},
  publisher    = {Oxford University Press},
  series       = {Nucleic Acids Research},
  title        = {HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis.},
  url          = {http://dx.doi.org/10.1093/nar/gks1021},
  volume       = {41},
  year         = {2013},
}