Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Physical performance tasks were linked to the PROMIS physical function metric in patients undergoing hemodialysis

Liegl, Gregor ; Fischer, Felix H. ; Woodward, Mark ; Török, Marietta ; Strippoli, Giovanni F.M. ; Hegbrant, Jörgen LU ; Davenport, Andrew ; Cromm, Krister ; Canaud, Bernard and Bots, Michiel L. , et al. (2023) In Journal of Clinical Epidemiology 159. p.128-138
Abstract

Objectives: To investigate whether a multi-item performance outcome measure, the physical performance test (PPT), can be calibrated to a common scale with patient-reported outcome measures, using the Patient-Reported Outcomes Measurement Information System (PROMIS) physical function (PF) metric. Study Design and Setting: We analyzed baseline data (N = 1,113) from the CONVINCE study, an international trial in end-stage kidney disease patients comparing high-dose hemodiafiltration with high-flux hemodialysis. Assumptions of item response theory (IRT) modelling were investigated for the combined set of the nine-item PPT and a four-item PROMIS PF short form (PROMIS-PF4a). We applied unidimensional IRT linking for calibrating the PPT to the... (More)

Objectives: To investigate whether a multi-item performance outcome measure, the physical performance test (PPT), can be calibrated to a common scale with patient-reported outcome measures, using the Patient-Reported Outcomes Measurement Information System (PROMIS) physical function (PF) metric. Study Design and Setting: We analyzed baseline data (N = 1,113) from the CONVINCE study, an international trial in end-stage kidney disease patients comparing high-dose hemodiafiltration with high-flux hemodialysis. Assumptions of item response theory (IRT) modelling were investigated for the combined set of the nine-item PPT and a four-item PROMIS PF short form (PROMIS-PF4a). We applied unidimensional IRT linking for calibrating the PPT to the PROMIS PF metric. Results: Although some evidence for multidimensionality was found, classical test statistics (Cronbach's Alpha = 0.93), Mokken (Loevinger's H = 0.50), and bifactor analysis (explained common variance = 0.65) indicated that PPT and PROMIS-PF4a items can be used to assess a common PF construct. On the group level, the agreement between PROMIS-PF4a and linked PPT scores was stable across several subsamples. On the individual level, scores differed considerably. Conclusion: We found preliminary evidence that the PPT can be linked to the PROMIS PF metric in hemodialysis patients, enabling group comparisons across patient-reported outcome and performance outcome measures. Alternative linking methods should be applied in future studies using a more comprehensive PROMIS PF item set.

(Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; ; ; ; and , et al. (More)
; ; ; ; ; ; ; ; ; ; ; ; and (Less)
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Clinical outcome assessment, Hemodialysis, Linking, Patient-reported outcomes, Performance outcomes, Physical function
in
Journal of Clinical Epidemiology
volume
159
pages
11 pages
publisher
Elsevier
external identifiers
  • pmid:37105321
  • scopus:85162167612
ISSN
0895-4356
DOI
10.1016/j.jclinepi.2023.04.007
language
English
LU publication?
yes
id
8416d010-0d10-47d7-9963-92cf23e1b26d
date added to LUP
2023-09-15 11:00:34
date last changed
2024-04-20 03:22:03
@article{8416d010-0d10-47d7-9963-92cf23e1b26d,
  abstract     = {{<p>Objectives: To investigate whether a multi-item performance outcome measure, the physical performance test (PPT), can be calibrated to a common scale with patient-reported outcome measures, using the Patient-Reported Outcomes Measurement Information System (PROMIS) physical function (PF) metric. Study Design and Setting: We analyzed baseline data (N = 1,113) from the CONVINCE study, an international trial in end-stage kidney disease patients comparing high-dose hemodiafiltration with high-flux hemodialysis. Assumptions of item response theory (IRT) modelling were investigated for the combined set of the nine-item PPT and a four-item PROMIS PF short form (PROMIS-PF4a). We applied unidimensional IRT linking for calibrating the PPT to the PROMIS PF metric. Results: Although some evidence for multidimensionality was found, classical test statistics (Cronbach's Alpha = 0.93), Mokken (Loevinger's H = 0.50), and bifactor analysis (explained common variance = 0.65) indicated that PPT and PROMIS-PF4a items can be used to assess a common PF construct. On the group level, the agreement between PROMIS-PF4a and linked PPT scores was stable across several subsamples. On the individual level, scores differed considerably. Conclusion: We found preliminary evidence that the PPT can be linked to the PROMIS PF metric in hemodialysis patients, enabling group comparisons across patient-reported outcome and performance outcome measures. Alternative linking methods should be applied in future studies using a more comprehensive PROMIS PF item set.</p>}},
  author       = {{Liegl, Gregor and Fischer, Felix H. and Woodward, Mark and Török, Marietta and Strippoli, Giovanni F.M. and Hegbrant, Jörgen and Davenport, Andrew and Cromm, Krister and Canaud, Bernard and Bots, Michiel L. and Blankestijn, Peter J. and Barth, Claudia and Fischer, Kathrin I. and Rose, Matthias}},
  issn         = {{0895-4356}},
  keywords     = {{Clinical outcome assessment; Hemodialysis; Linking; Patient-reported outcomes; Performance outcomes; Physical function}},
  language     = {{eng}},
  pages        = {{128--138}},
  publisher    = {{Elsevier}},
  series       = {{Journal of Clinical Epidemiology}},
  title        = {{Physical performance tasks were linked to the PROMIS physical function metric in patients undergoing hemodialysis}},
  url          = {{http://dx.doi.org/10.1016/j.jclinepi.2023.04.007}},
  doi          = {{10.1016/j.jclinepi.2023.04.007}},
  volume       = {{159}},
  year         = {{2023}},
}