A biokinetic study of (209)Po in man.
Henricsson, Fredrik LU ; Ranebo, Ylva LU ; Hansson, Mats LU ; Rääf, Christopher LU
and Holm, Elis
(2012)
In Science of the Total Environment
437C.
p.384-389
- Abstract
- Five adult volunteers participated in a biokinetic study of radioactive polonium. Portions of about 10Bq of (209)Po were orally administrated to four of the volunteers in a single ingestion. The fifth volunteer ingested a daily amount of 53mBq of 209Po for 243d to study the time to achieve equilibrium between intake and excretion for protracted intakes. For the subjects ingesting single intakes of (209)Po complete sampling of urine and feces was subsequently collected the first few days upon the ingestion. The samples were processed with radiochemical extraction and analyzed with alpha spectrometry. In the study, the maximum daily excretion rates in feces were 18-50% of the ingested activity, observed within 3d after intake. Regarding the... (More)
- Five adult volunteers participated in a biokinetic study of radioactive polonium. Portions of about 10Bq of (209)Po were orally administrated to four of the volunteers in a single ingestion. The fifth volunteer ingested a daily amount of 53mBq of 209Po for 243d to study the time to achieve equilibrium between intake and excretion for protracted intakes. For the subjects ingesting single intakes of (209)Po complete sampling of urine and feces was subsequently collected the first few days upon the ingestion. The samples were processed with radiochemical extraction and analyzed with alpha spectrometry. In the study, the maximum daily excretion rates in feces were 18-50% of the ingested activity, observed within 3d after intake. Regarding the urine excretion, the daily excretion peaked, on average, at 0.15-1% of the ingested activity within two days upon intake. These results indicate an average gastro-intestinal uptake fraction of 0.46±0.08, which agrees well with earlier biokinetic studies of polonium in man. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3124113
- author
- Henricsson, Fredrik
LU
; Ranebo, Ylva
LU
; Hansson, Mats
LU
; Rääf, Christopher
LU
and Holm, Elis
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Biokinetics, Polonium, Po-209, Biological half-time, Metabolism, Uptake, fraction
- in
- Science of the Total Environment
- volume
- 437C
- pages
- 384 - 389
- publisher
- Elsevier
- external identifiers
-
- wos:000310941000044
- pmid:22960113
- scopus:84865657713
- pmid:22960113
- ISSN
- 1879-1026
- DOI
- 10.1016/j.scitotenv.2012.07.080
- language
- English
- LU publication?
- yes
- id
- 842da5ea-d42c-4d8b-bf1d-42aa9bc62767 (old id 3124113)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/22960113?dopt=Abstract
- date added to LUP
- 2016-04-01 10:46:01
- date last changed
- 2024-04-07 16:36:55
@article{842da5ea-d42c-4d8b-bf1d-42aa9bc62767,
abstract = {{Five adult volunteers participated in a biokinetic study of radioactive polonium. Portions of about 10Bq of (209)Po were orally administrated to four of the volunteers in a single ingestion. The fifth volunteer ingested a daily amount of 53mBq of 209Po for 243d to study the time to achieve equilibrium between intake and excretion for protracted intakes. For the subjects ingesting single intakes of (209)Po complete sampling of urine and feces was subsequently collected the first few days upon the ingestion. The samples were processed with radiochemical extraction and analyzed with alpha spectrometry. In the study, the maximum daily excretion rates in feces were 18-50% of the ingested activity, observed within 3d after intake. Regarding the urine excretion, the daily excretion peaked, on average, at 0.15-1% of the ingested activity within two days upon intake. These results indicate an average gastro-intestinal uptake fraction of 0.46±0.08, which agrees well with earlier biokinetic studies of polonium in man.}},
author = {{Henricsson, Fredrik and Ranebo, Ylva and Hansson, Mats and Rääf, Christopher and Holm, Elis}},
issn = {{1879-1026}},
keywords = {{Biokinetics; Polonium; Po-209; Biological half-time; Metabolism; Uptake; fraction}},
language = {{eng}},
pages = {{384--389}},
publisher = {{Elsevier}},
series = {{Science of the Total Environment}},
title = {{A biokinetic study of (209)Po in man.}},
url = {{http://dx.doi.org/10.1016/j.scitotenv.2012.07.080}},
doi = {{10.1016/j.scitotenv.2012.07.080}},
volume = {{437C}},
year = {{2012}},
}