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Delayed cord clamping was not associated with an increased risk of hyperbilirubinaemia on the day of birth or jaundice in the first 4 weeks

Rana, Nisha ; Ranneberg, Linda Jarawka ; Målqvist, Mats ; Kc, Ashish and Andersson, Ola LU orcid (2020) In Acta Pædiatrica 109(1). p.71-77
Abstract

AIM: Our aim was to investigate the effects of timing of cord clamping on the risk of hyperbilirubinaemia.

METHODS: We recruited 540 normal vaginal deliveries at the Paropakar Maternity and Women's Hospital in Kathmandu, Nepal, from 2 October to 21 November 2014. They were randomised into two groups: 257/270 were cord clamped within 60 seconds and 209/270 after 180 seconds. Transcutaneous bilirubin was measured at discharge and 24 hours. At four weeks, 506 mothers were successfully contacted by phone and the health status of the baby and their history of jaundice and treatment was recorded.

RESULTS: Based on transcutaneous bilirubin at discharge, 22/261 (8.4%) in the early group and 25/263 (9.5%) in the delayed group... (More)

AIM: Our aim was to investigate the effects of timing of cord clamping on the risk of hyperbilirubinaemia.

METHODS: We recruited 540 normal vaginal deliveries at the Paropakar Maternity and Women's Hospital in Kathmandu, Nepal, from 2 October to 21 November 2014. They were randomised into two groups: 257/270 were cord clamped within 60 seconds and 209/270 after 180 seconds. Transcutaneous bilirubin was measured at discharge and 24 hours. At four weeks, 506 mothers were successfully contacted by phone and the health status of the baby and their history of jaundice and treatment was recorded.

RESULTS: Based on transcutaneous bilirubin at discharge, 22/261 (8.4%) in the early group and 25/263 (9.5%) in the delayed group (p=0.76) were at high risk of subsequent hyperbilirubinemia. At the four-week follow up, jaundice was reported in 13/253 (5.1%) in the early and 17/253 (6.7%) in the delayed group (p=0.57) and 3/253 (1.2 %) of the early and 1/253 (0.4%) of the delayed group (p= 0.62) received treatment. All analyses were based on intention-to-treat.

CONCLUSION: Delayed cord clamping was not associated with an increased risk of hyperbilirubinaemia during the first day of life or risk of jaundice within four weeks compared with the early group. This article is protected by copyright. All rights reserved.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Pædiatrica
volume
109
issue
1
pages
71 - 77
publisher
Wiley-Blackwell
external identifiers
  • pmid:31240753
  • scopus:85069916549
ISSN
1651-2227
DOI
10.1111/apa.14913
language
English
LU publication?
yes
additional info
This article is protected by copyright. All rights reserved.
id
847b87f5-1d21-47dc-9c72-9f683f30279c
date added to LUP
2019-07-02 09:46:26
date last changed
2024-04-16 13:23:48
@article{847b87f5-1d21-47dc-9c72-9f683f30279c,
  abstract     = {{<p>AIM: Our aim was to investigate the effects of timing of cord clamping on the risk of hyperbilirubinaemia.</p><p>METHODS: We recruited 540 normal vaginal deliveries at the Paropakar Maternity and Women's Hospital in Kathmandu, Nepal, from 2 October to 21 November 2014. They were randomised into two groups: 257/270 were cord clamped within 60 seconds and 209/270 after 180 seconds. Transcutaneous bilirubin was measured at discharge and 24 hours. At four weeks, 506 mothers were successfully contacted by phone and the health status of the baby and their history of jaundice and treatment was recorded.</p><p>RESULTS: Based on transcutaneous bilirubin at discharge, 22/261 (8.4%) in the early group and 25/263 (9.5%) in the delayed group (p=0.76) were at high risk of subsequent hyperbilirubinemia. At the four-week follow up, jaundice was reported in 13/253 (5.1%) in the early and 17/253 (6.7%) in the delayed group (p=0.57) and 3/253 (1.2 %) of the early and 1/253 (0.4%) of the delayed group (p= 0.62) received treatment. All analyses were based on intention-to-treat.</p><p>CONCLUSION: Delayed cord clamping was not associated with an increased risk of hyperbilirubinaemia during the first day of life or risk of jaundice within four weeks compared with the early group. This article is protected by copyright. All rights reserved.</p>}},
  author       = {{Rana, Nisha and Ranneberg, Linda Jarawka and Målqvist, Mats and Kc, Ashish and Andersson, Ola}},
  issn         = {{1651-2227}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{71--77}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Acta Pædiatrica}},
  title        = {{Delayed cord clamping was not associated with an increased risk of hyperbilirubinaemia on the day of birth or jaundice in the first 4 weeks}},
  url          = {{http://dx.doi.org/10.1111/apa.14913}},
  doi          = {{10.1111/apa.14913}},
  volume       = {{109}},
  year         = {{2020}},
}