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Short-term adaptation during propagation improves the performance of xylose-fermenting Saccharomyces cerevisiae in simultaneous saccharification and co-fermentation.

Nielsen, Fredrik LU ; Tomás-Pejó, Elia; Olsson, Lisbeth and Wallberg, Ola LU (2015) In Biotechnology for Biofuels 8.
Abstract
Inhibitors that are generated during thermochemical pretreatment and hydrolysis impair the performance of microorganisms during fermentation of lignocellulosic hydrolysates. In omitting costly detoxification steps, the fermentation process relies extensively on the performance of the fermenting microorganism. One attractive option of improving its performance and tolerance to microbial inhibitors is short-term adaptation during propagation. This study determined the influence of short-term adaptation on the performance of recombinant Saccharomyces cerevisiae in simultaneous saccharification and co-fermentation (SSCF). The aim was to understand how short-term adaptation with lignocellulosic hydrolysate affects the cell mass yield of... (More)
Inhibitors that are generated during thermochemical pretreatment and hydrolysis impair the performance of microorganisms during fermentation of lignocellulosic hydrolysates. In omitting costly detoxification steps, the fermentation process relies extensively on the performance of the fermenting microorganism. One attractive option of improving its performance and tolerance to microbial inhibitors is short-term adaptation during propagation. This study determined the influence of short-term adaptation on the performance of recombinant Saccharomyces cerevisiae in simultaneous saccharification and co-fermentation (SSCF). The aim was to understand how short-term adaptation with lignocellulosic hydrolysate affects the cell mass yield of propagated yeast and performance in subsequent fermentation steps. The physiology of propagated yeast was examined with regard to viability, vitality, stress responses, and upregulation of relevant genes to identify any links between the beneficial traits that are promoted during adaptation and overall ethanol yields in co-fermentation. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Biotechnology for Biofuels
volume
8
publisher
BioMed Central
external identifiers
  • pmid:26697108
  • wos:000367227500003
  • scopus:84954075853
ISSN
1754-6834
DOI
10.1186/s13068-015-0399-4
language
English
LU publication?
yes
id
42e35f23-4355-496d-9e6c-744b92b7aa48 (old id 8503848)
date added to LUP
2016-01-07 17:12:08
date last changed
2017-10-01 04:27:49
@article{42e35f23-4355-496d-9e6c-744b92b7aa48,
  abstract     = {Inhibitors that are generated during thermochemical pretreatment and hydrolysis impair the performance of microorganisms during fermentation of lignocellulosic hydrolysates. In omitting costly detoxification steps, the fermentation process relies extensively on the performance of the fermenting microorganism. One attractive option of improving its performance and tolerance to microbial inhibitors is short-term adaptation during propagation. This study determined the influence of short-term adaptation on the performance of recombinant Saccharomyces cerevisiae in simultaneous saccharification and co-fermentation (SSCF). The aim was to understand how short-term adaptation with lignocellulosic hydrolysate affects the cell mass yield of propagated yeast and performance in subsequent fermentation steps. The physiology of propagated yeast was examined with regard to viability, vitality, stress responses, and upregulation of relevant genes to identify any links between the beneficial traits that are promoted during adaptation and overall ethanol yields in co-fermentation.},
  articleno    = {219},
  author       = {Nielsen, Fredrik and Tomás-Pejó, Elia and Olsson, Lisbeth and Wallberg, Ola},
  issn         = {1754-6834},
  language     = {eng},
  publisher    = {BioMed Central},
  series       = {Biotechnology for Biofuels},
  title        = {Short-term adaptation during propagation improves the performance of xylose-fermenting Saccharomyces cerevisiae in simultaneous saccharification and co-fermentation.},
  url          = {http://dx.doi.org/10.1186/s13068-015-0399-4},
  volume       = {8},
  year         = {2015},
}