Advanced

Early diagnosis of primary Sjögren's syndrome: EULAR-SS task force clinical recommendations.

Brito-Zerón, Pilar; Theander, Elke LU ; Baldini, Chiara; Seror, Raphaèle; Retamozo, Soledad; Quartuccio, Luca; Bootsma, Hendrika; Bowman, Simon J; Dörner, Thomas and Gottenberg, Jacques-Eric, et al. (2016) In Expert Review of Clinical Immunology 12(2). p.137-156
Abstract
Sjögren's syndrome (SjS) is a systemic autoimmune disease that mainly affects the exocrine glands, leading to generalized mucosal dryness. However, primary SjS may initially present with non-sicca (systemic) manifestations. When these features appear before the onset of an overt sicca syndrome, we may talk of an underlying 'occult' SjS. The European League Against Rheumatism (EULAR) has promoted and supported an international collaborative study group (EULAR-SS Task Force) aimed at developing consensual recommendations to provide a homogeneous approach to the patient with primary SjS presenting with systemic involvement. This review summarizes the key factors that should be taken into account in the diagnostic approach in a patient with... (More)
Sjögren's syndrome (SjS) is a systemic autoimmune disease that mainly affects the exocrine glands, leading to generalized mucosal dryness. However, primary SjS may initially present with non-sicca (systemic) manifestations. When these features appear before the onset of an overt sicca syndrome, we may talk of an underlying 'occult' SjS. The European League Against Rheumatism (EULAR) has promoted and supported an international collaborative study group (EULAR-SS Task Force) aimed at developing consensual recommendations to provide a homogeneous approach to the patient with primary SjS presenting with systemic involvement. This review summarizes the key factors that should be taken into account in the diagnostic approach in a patient with suspected SjS according to the main clinical patterns of presentation, and is especially focused on organ-specific systemic disease presentations, including a consensus set of recommendations in order to reach an early diagnosis. Close collaboration with the different specialties involved through a comprehensive multidisciplinary approach is essential in SjS patients presenting with systemic involvements. (Less)
Please use this url to cite or link to this publication:
author
, et al. (More)
(Less)
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Expert Review of Clinical Immunology
volume
12
issue
2
pages
137 - 156
publisher
Expert Reviews
external identifiers
  • pmid:26691952
  • scopus:84957431999
  • wos:000370277200001
ISSN
1744-8409
DOI
10.1586/1744666X.2016.1109449
language
English
LU publication?
yes
id
71ffd002-0afb-40ce-aa51-b4626b360743 (old id 8503990)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26691952?dopt=Abstract
date added to LUP
2016-01-06 12:16:13
date last changed
2017-11-05 04:41:50
@article{71ffd002-0afb-40ce-aa51-b4626b360743,
  abstract     = {Sjögren's syndrome (SjS) is a systemic autoimmune disease that mainly affects the exocrine glands, leading to generalized mucosal dryness. However, primary SjS may initially present with non-sicca (systemic) manifestations. When these features appear before the onset of an overt sicca syndrome, we may talk of an underlying 'occult' SjS. The European League Against Rheumatism (EULAR) has promoted and supported an international collaborative study group (EULAR-SS Task Force) aimed at developing consensual recommendations to provide a homogeneous approach to the patient with primary SjS presenting with systemic involvement. This review summarizes the key factors that should be taken into account in the diagnostic approach in a patient with suspected SjS according to the main clinical patterns of presentation, and is especially focused on organ-specific systemic disease presentations, including a consensus set of recommendations in order to reach an early diagnosis. Close collaboration with the different specialties involved through a comprehensive multidisciplinary approach is essential in SjS patients presenting with systemic involvements.},
  author       = {Brito-Zerón, Pilar and Theander, Elke and Baldini, Chiara and Seror, Raphaèle and Retamozo, Soledad and Quartuccio, Luca and Bootsma, Hendrika and Bowman, Simon J and Dörner, Thomas and Gottenberg, Jacques-Eric and Mariette, Xavier and Bombardieri, Stefano and de Vita, Salvatore and Mandl, Thomas and Ng, Wan-Fai and Kruize, Aike A and Tzioufas, Athanasios and Vitali, Claudio and Buyon, Jill and Izmirly, Peter and Fox, Robert and Ramos-Casals, Manuel and On Behalf Of The Eular Sjögren Syndrome Task Force, NN},
  issn         = {1744-8409},
  language     = {eng},
  number       = {2},
  pages        = {137--156},
  publisher    = {Expert Reviews},
  series       = {Expert Review of Clinical Immunology},
  title        = {Early diagnosis of primary Sjögren's syndrome: EULAR-SS task force clinical recommendations.},
  url          = {http://dx.doi.org/10.1586/1744666X.2016.1109449},
  volume       = {12},
  year         = {2016},
}