Gene variance in the nicotinic receptor cluster (CHRNA5-CHRNA3-CHRNB4) predicts death from cardiopulmonary disease and cancer in smokers.
(2016) In Journal of Internal Medicine 279(4). p.388-398- Abstract
- Genetic variation in the cluster on chromosome 15, encoding the nicotinic acetylcholine receptor subunits (CHRNA5-CHRNA3-CHRNB4), has shown strong associations with tobacco consumption and an additional risk increase in smoking-related diseases such as chronic obstructive pulmonary disease (COPD), peripheral artery disease and lung cancer.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8504120
- author
- Halldén, Sara LU ; Sjögren, Marketa LU ; Hedblad, Bo LU ; Engström, Gunnar LU ; Hamrefors, Viktor LU ; Manjer, Jonas LU and Melander, Olle LU
- organization
- publishing date
- 2016
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Internal Medicine
- volume
- 279
- issue
- 4
- pages
- 388 - 398
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:26689306
- scopus:84961200060
- wos:000372978800008
- pmid:26689306
- ISSN
- 1365-2796
- DOI
- 10.1111/joim.12454
- language
- English
- LU publication?
- yes
- id
- cb7c608e-c1e5-442a-94cd-a45ea904214f (old id 8504120)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26689306?dopt=Abstract
- date added to LUP
- 2016-04-04 09:11:21
- date last changed
- 2024-05-11 05:52:38
@article{cb7c608e-c1e5-442a-94cd-a45ea904214f, abstract = {{Genetic variation in the cluster on chromosome 15, encoding the nicotinic acetylcholine receptor subunits (CHRNA5-CHRNA3-CHRNB4), has shown strong associations with tobacco consumption and an additional risk increase in smoking-related diseases such as chronic obstructive pulmonary disease (COPD), peripheral artery disease and lung cancer.}}, author = {{Halldén, Sara and Sjögren, Marketa and Hedblad, Bo and Engström, Gunnar and Hamrefors, Viktor and Manjer, Jonas and Melander, Olle}}, issn = {{1365-2796}}, language = {{eng}}, number = {{4}}, pages = {{388--398}}, publisher = {{Wiley-Blackwell}}, series = {{Journal of Internal Medicine}}, title = {{Gene variance in the nicotinic receptor cluster (CHRNA5-CHRNA3-CHRNB4) predicts death from cardiopulmonary disease and cancer in smokers.}}, url = {{http://dx.doi.org/10.1111/joim.12454}}, doi = {{10.1111/joim.12454}}, volume = {{279}}, year = {{2016}}, }