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Concise Total Synthesis of Dehaloperophoramidine.

Popov, Kirill LU ; Hoang, Anita LU and Somfai, Peter LU (2015) In Angewandte Chemie (International edition)
Abstract
Perophoramidine, dehaloperophoramidine, and communesin F are structurally related alkaloids having intriguing polycyclic structures. A strategy for the synthesis of dehaloperophoramidine has been developed. In this synthesis all skeletal atoms and all functional groups required to reach the target molecule are incorporated early in the sequence. This approach led to the discovery of two novel substrate-specific domino processes, one encompassing four steps and the other comprising five steps, thus resulting in an eight-step synthesis of dehaloperophoramidine.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Angewandte Chemie (International edition)
publisher
John Wiley & Sons
external identifiers
  • pmid:26676910
  • scopus:84955704958
  • wos:000369854000036
ISSN
1521-3773
DOI
10.1002/anie.201510661
language
English
LU publication?
yes
id
a641eecf-3514-44bb-aa5d-00a05970b564 (old id 8504438)
date added to LUP
2016-01-13 11:19:50
date last changed
2017-08-20 04:01:24
@article{a641eecf-3514-44bb-aa5d-00a05970b564,
  abstract     = {Perophoramidine, dehaloperophoramidine, and communesin F are structurally related alkaloids having intriguing polycyclic structures. A strategy for the synthesis of dehaloperophoramidine has been developed. In this synthesis all skeletal atoms and all functional groups required to reach the target molecule are incorporated early in the sequence. This approach led to the discovery of two novel substrate-specific domino processes, one encompassing four steps and the other comprising five steps, thus resulting in an eight-step synthesis of dehaloperophoramidine.},
  author       = {Popov, Kirill and Hoang, Anita and Somfai, Peter},
  issn         = {1521-3773},
  language     = {eng},
  month        = {12},
  publisher    = {John Wiley & Sons},
  series       = {Angewandte Chemie (International edition)},
  title        = {Concise Total Synthesis of Dehaloperophoramidine.},
  url          = {http://dx.doi.org/10.1002/anie.201510661},
  year         = {2015},
}