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Microsurgical Subinguinal Varicocele Repair of Grade II-III Lesions Associated with Improvements of Testosterone Levels

Elzanaty, Saad LU and Johansen, Claus Erik (2017) In Current Urology 10(1). p.45-49
Abstract

Introduction: The results of reports on the association between varicocele repair and testosterone levels were conflicting. The aim of the present study is, therefore, to investigate the impact of varicocele repair on testosterone levels. Materials and Methods: The study is based on 20 men who experienced microsurgical subinguinal varicoceles repair because of chronic dull scrotal pain. All hormonal profiles available in the clinical records were reviewed. Follow-up evaluation was done at 1 and 12 months after surgery. Men were classified into groups based on the preoperative testosterone levels: euogonadal (serum levels of testosterone > 12 nmol/l), hypogonadal men (serum levels of testosterone ≤ 12 nmol/l). Results: Microsurgical... (More)

Introduction: The results of reports on the association between varicocele repair and testosterone levels were conflicting. The aim of the present study is, therefore, to investigate the impact of varicocele repair on testosterone levels. Materials and Methods: The study is based on 20 men who experienced microsurgical subinguinal varicoceles repair because of chronic dull scrotal pain. All hormonal profiles available in the clinical records were reviewed. Follow-up evaluation was done at 1 and 12 months after surgery. Men were classified into groups based on the preoperative testosterone levels: euogonadal (serum levels of testosterone > 12 nmol/l), hypogonadal men (serum levels of testosterone ≤ 12 nmol/l). Results: Microsurgical subinguinal varicocele repair was associated with a significant improvements of testosterone levels at 1 and 12 months after surgery as compared to the preoperative levels (13 nmol/l vs. 18 nmol/l, p = 0.03; 13 nmol/l vs. 15 nmol/l, p = 0.01). The same trend was seen in men who were classified as being hypogonadal (7.0 nmol/l vs. 15 nmol/l, p = 0.01; 7.0 nmol/l vs. 10 nmol/l, p = 0.02). No significant improvements in testosterone levels were observed in euogonadal men (p > 0.05). Conclusion: Microsurgical subinguinal varicocele repair was associated with a significant improvements of testosterone levels in men with grade II-III lesions and low preoperative testosterone values.

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author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Hypogonadism, Microsurgery, Testosterone, Varicocele repair
in
Current Urology
volume
10
issue
1
pages
5 pages
publisher
Karger
external identifiers
  • pmid:28559777
  • scopus:85022229550
ISSN
1661-7649
DOI
10.1159/000447150
language
English
LU publication?
yes
id
850abee6-6abd-4c0b-b28a-ed5640552c75
date added to LUP
2017-07-25 13:20:08
date last changed
2025-01-07 17:43:06
@article{850abee6-6abd-4c0b-b28a-ed5640552c75,
  abstract     = {{<p>Introduction: The results of reports on the association between varicocele repair and testosterone levels were conflicting. The aim of the present study is, therefore, to investigate the impact of varicocele repair on testosterone levels. Materials and Methods: The study is based on 20 men who experienced microsurgical subinguinal varicoceles repair because of chronic dull scrotal pain. All hormonal profiles available in the clinical records were reviewed. Follow-up evaluation was done at 1 and 12 months after surgery. Men were classified into groups based on the preoperative testosterone levels: euogonadal (serum levels of testosterone &gt; 12 nmol/l), hypogonadal men (serum levels of testosterone ≤ 12 nmol/l). Results: Microsurgical subinguinal varicocele repair was associated with a significant improvements of testosterone levels at 1 and 12 months after surgery as compared to the preoperative levels (13 nmol/l vs. 18 nmol/l, p = 0.03; 13 nmol/l vs. 15 nmol/l, p = 0.01). The same trend was seen in men who were classified as being hypogonadal (7.0 nmol/l vs. 15 nmol/l, p = 0.01; 7.0 nmol/l vs. 10 nmol/l, p = 0.02). No significant improvements in testosterone levels were observed in euogonadal men (p &gt; 0.05). Conclusion: Microsurgical subinguinal varicocele repair was associated with a significant improvements of testosterone levels in men with grade II-III lesions and low preoperative testosterone values.</p>}},
  author       = {{Elzanaty, Saad and Johansen, Claus Erik}},
  issn         = {{1661-7649}},
  keywords     = {{Hypogonadism; Microsurgery; Testosterone; Varicocele repair}},
  language     = {{eng}},
  month        = {{07}},
  number       = {{1}},
  pages        = {{45--49}},
  publisher    = {{Karger}},
  series       = {{Current Urology}},
  title        = {{Microsurgical Subinguinal Varicocele Repair of Grade II-III Lesions Associated with Improvements of Testosterone Levels}},
  url          = {{http://dx.doi.org/10.1159/000447150}},
  doi          = {{10.1159/000447150}},
  volume       = {{10}},
  year         = {{2017}},
}