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Improved Liver Lesion Conspicuity With Iterative Reconstruction in Computed Tomography Imaging.

Jensen, Kristin; Andersen, Hilde Kjernlie; Tingberg, Anders LU ; Reisse, Claudius; Fosse, Erik and Martinsen, Anne Catrine T (2016) In Current Problems in Diagnostic Radiology 45(5). p.291-296
Abstract
Studies on iterative reconstruction techniques on computed tomographic (CT) scanners show reduced noise and changed image texture. The purpose of this study was to address the possibility of dose reduction and improved conspicuity of lesions in a liver phantom for different iterative reconstruction algorithms. An anthropomorphic upper abdomen phantom, specially designed for receiver operating characteristic analysis was scanned with 2 different CT models from the same vendor, GE CT750 HD and GE Lightspeed VCT. Images were obtained at 3 dose levels, 5, 10, and 15mGy, and reconstructed with filtered back projection (FBP), and 2 different iterative reconstruction algorithms; adaptive statistical iterative reconstruction and Veo. Overall, 5... (More)
Studies on iterative reconstruction techniques on computed tomographic (CT) scanners show reduced noise and changed image texture. The purpose of this study was to address the possibility of dose reduction and improved conspicuity of lesions in a liver phantom for different iterative reconstruction algorithms. An anthropomorphic upper abdomen phantom, specially designed for receiver operating characteristic analysis was scanned with 2 different CT models from the same vendor, GE CT750 HD and GE Lightspeed VCT. Images were obtained at 3 dose levels, 5, 10, and 15mGy, and reconstructed with filtered back projection (FBP), and 2 different iterative reconstruction algorithms; adaptive statistical iterative reconstruction and Veo. Overall, 5 interpreters evaluated the images and receiver operating characteristic analysis was performed. Standard deviation and the contrast to noise ratio were measured. Veo image reconstruction resulted in larger area under curves compared with those adaptive statistical iterative reconstruction and FBP image reconstruction for given dose levels. For the CT750 HD, iterative reconstruction at the 10mGy dose level resulted in larger or similar area under curves compared with FBP at the 15mGy dose level (0.88-0.95 vs 0.90). This was not shown for the Lightspeed VCT (0.83-0.85 vs 0.92). The results in this study indicate that the possibility for radiation dose reduction using iterative reconstruction techniques depends on both reconstruction technique and the CT scanner model used. (Less)
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author
organization
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type
Contribution to journal
publication status
published
subject
in
Current Problems in Diagnostic Radiology
volume
45
issue
5
pages
291 - 296
publisher
Mosby Inc.
external identifiers
  • pmid:26790606
  • scopus:84953774998
ISSN
0363-0188
DOI
10.1067/j.cpradiol.2015.11.004
language
English
LU publication?
yes
id
bcf141b2-35d5-48d2-ba41-715eff90973c (old id 8576814)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26790606?dopt=Abstract
date added to LUP
2016-02-10 12:37:36
date last changed
2017-05-04 13:10:38
@article{bcf141b2-35d5-48d2-ba41-715eff90973c,
  abstract     = {Studies on iterative reconstruction techniques on computed tomographic (CT) scanners show reduced noise and changed image texture. The purpose of this study was to address the possibility of dose reduction and improved conspicuity of lesions in a liver phantom for different iterative reconstruction algorithms. An anthropomorphic upper abdomen phantom, specially designed for receiver operating characteristic analysis was scanned with 2 different CT models from the same vendor, GE CT750 HD and GE Lightspeed VCT. Images were obtained at 3 dose levels, 5, 10, and 15mGy, and reconstructed with filtered back projection (FBP), and 2 different iterative reconstruction algorithms; adaptive statistical iterative reconstruction and Veo. Overall, 5 interpreters evaluated the images and receiver operating characteristic analysis was performed. Standard deviation and the contrast to noise ratio were measured. Veo image reconstruction resulted in larger area under curves compared with those adaptive statistical iterative reconstruction and FBP image reconstruction for given dose levels. For the CT750 HD, iterative reconstruction at the 10mGy dose level resulted in larger or similar area under curves compared with FBP at the 15mGy dose level (0.88-0.95 vs 0.90). This was not shown for the Lightspeed VCT (0.83-0.85 vs 0.92). The results in this study indicate that the possibility for radiation dose reduction using iterative reconstruction techniques depends on both reconstruction technique and the CT scanner model used.},
  author       = {Jensen, Kristin and Andersen, Hilde Kjernlie and Tingberg, Anders and Reisse, Claudius and Fosse, Erik and Martinsen, Anne Catrine T},
  issn         = {0363-0188},
  language     = {eng},
  number       = {5},
  pages        = {291--296},
  publisher    = {Mosby Inc.},
  series       = {Current Problems in Diagnostic Radiology},
  title        = {Improved Liver Lesion Conspicuity With Iterative Reconstruction in Computed Tomography Imaging.},
  url          = {http://dx.doi.org/10.1067/j.cpradiol.2015.11.004},
  volume       = {45},
  year         = {2016},
}