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Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson's disease.

Majbour, Nour K; Vaikath, Nishant N. LU ; van Dijk, Karin D; Ardah, Mustafa T; Varghese, Shiji; Vesterager, Louise B; Montezinho, Liliana P; Poole, Stephen; Safieh-Garabedian, Bared and Tokuda, Takahiko, et al. (2016) In Molecular Neurodegeneration 11(1).
Abstract
Despite decades of intensive research, to date, there is no accepted diagnosis for Parkinson's disease (PD) based on biochemical analysis of blood or CSF. However, neurodegeneration in the brains of PD patients begins several years before the manifestation of the clinical symptoms, pointing to serious flaw/limitations in this approach.
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publication status
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Molecular Neurodegeneration
volume
11
issue
1
publisher
BioMed Central
external identifiers
  • pmid:26782965
  • wos:000368974800001
  • scopus:84954348724
ISSN
1750-1326
DOI
10.1186/s13024-016-0072-9
language
English
LU publication?
yes
id
8dd20982-3de5-4550-a8e6-92261ef9cd58 (old id 8577042)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26782965?dopt=Abstract
date added to LUP
2016-02-03 18:33:08
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2017-11-12 03:41:25
@article{8dd20982-3de5-4550-a8e6-92261ef9cd58,
  abstract     = {Despite decades of intensive research, to date, there is no accepted diagnosis for Parkinson's disease (PD) based on biochemical analysis of blood or CSF. However, neurodegeneration in the brains of PD patients begins several years before the manifestation of the clinical symptoms, pointing to serious flaw/limitations in this approach.},
  articleno    = {7},
  author       = {Majbour, Nour K and Vaikath, Nishant N. and van Dijk, Karin D and Ardah, Mustafa T and Varghese, Shiji and Vesterager, Louise B and Montezinho, Liliana P and Poole, Stephen and Safieh-Garabedian, Bared and Tokuda, Takahiko and Teunissen, Charlotte E and Berendse, Henk W and van de Berg, Wilma D J and El-Agnaf, Omar M A},
  issn         = {1750-1326},
  language     = {eng},
  number       = {1},
  publisher    = {BioMed Central},
  series       = {Molecular Neurodegeneration},
  title        = {Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson's disease.},
  url          = {http://dx.doi.org/10.1186/s13024-016-0072-9},
  volume       = {11},
  year         = {2016},
}