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Analysis of White Adipose Tissue Gene Expression Reveals CREB1 Pathway Altered in Huntington's Disease.

McCourt, Andy LU ; Parker, Jennifer; Silajdzic, Edina LU ; Haider, Salman; Sethi, Huma; Tabrizi, Sarah J; Warner, Thomas T and Björkqvist, Maria LU (2015) In Journal of Huntington's disease 4(4). p.371-382
Abstract
In addition to classical neurological symptoms, Huntington's disease (HD) is complicated by peripheral pathology and both the mutant gene and the protein are found in cells and tissues throughout the body. Despite the adipose tissue gene expression alterations described in HD mouse models, adipose tissue and its gene expression signature have not been previously explored in human HD.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Huntington's disease
volume
4
issue
4
pages
371 - 382
publisher
IOS Press
external identifiers
  • pmid:26756592
  • wos:000369571300008
  • scopus:84961711607
ISSN
1879-6397
DOI
10.3233/JHD-150172
language
English
LU publication?
yes
id
2b8abfcf-0ba7-40f2-8ed0-648821f587fe (old id 8592322)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26756592?dopt=Abstract
date added to LUP
2016-02-10 11:38:01
date last changed
2017-02-02 09:47:39
@article{2b8abfcf-0ba7-40f2-8ed0-648821f587fe,
  abstract     = {In addition to classical neurological symptoms, Huntington's disease (HD) is complicated by peripheral pathology and both the mutant gene and the protein are found in cells and tissues throughout the body. Despite the adipose tissue gene expression alterations described in HD mouse models, adipose tissue and its gene expression signature have not been previously explored in human HD.},
  author       = {McCourt, Andy and Parker, Jennifer and Silajdzic, Edina and Haider, Salman and Sethi, Huma and Tabrizi, Sarah J and Warner, Thomas T and Björkqvist, Maria},
  issn         = {1879-6397},
  language     = {eng},
  number       = {4},
  pages        = {371--382},
  publisher    = {IOS Press},
  series       = {Journal of Huntington's disease},
  title        = {Analysis of White Adipose Tissue Gene Expression Reveals CREB1 Pathway Altered in Huntington's Disease.},
  url          = {http://dx.doi.org/10.3233/JHD-150172},
  volume       = {4},
  year         = {2015},
}