Terahertz Spectroscopic Analysis of Lactose in Infant Formula : Implications for Detection and Quantification
(2022) In Molecules 27(15).- Abstract
Lactose plays a significant role in daily lives as a constituent of various food and pharmaceutical products. Yet, lactose intolerance conditions demand low-lactose and lactose-free products in the market. These increasing nutritional claims and labels on food products entail simple and reliable methods of analysis that can be used for meeting quality standards, nutritional claims and legal requirements. In this study, terahertz time–domain spectroscopy (THz-TDS) was employed to analyse α-lactose monohydrate qualitatively and quantitatively in food products. Both absorption spectra and absorption coefficient spectra were investigated for their prediction performance. Regression models for lactose quantification using peak area and... (More)
Lactose plays a significant role in daily lives as a constituent of various food and pharmaceutical products. Yet, lactose intolerance conditions demand low-lactose and lactose-free products in the market. These increasing nutritional claims and labels on food products entail simple and reliable methods of analysis that can be used for meeting quality standards, nutritional claims and legal requirements. In this study, terahertz time–domain spectroscopy (THz-TDS) was employed to analyse α-lactose monohydrate qualitatively and quantitatively in food products. Both absorption spectra and absorption coefficient spectra were investigated for their prediction performance. Regression models for lactose quantification using peak area and height of the absorption peaks 0.53 and 1.37 THz were developed and assessed in infant formula samples. Satisfactory prediction results were achieved in ideal conditions with pure standards, but not in all predictions of infant formula samples. Reasons and further implications are discussed.
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- author
- Datta, Sopanant ; Prasertsuk, Kiattiwut ; Khammata, Nuttawat ; Rattanawan, Patharakorn ; Chia, Jia Yi ; Jintamethasawat, Rungroj ; Chulapakorn, Thawatchart LU and Limpanuparb, Taweetham
- organization
- publishing date
- 2022
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- lactose quantification, Terahertz time–domain spectroscopy, α-lactose monohydrate
- in
- Molecules
- volume
- 27
- issue
- 15
- article number
- 5040
- publisher
- MDPI AG
- external identifiers
-
- pmid:35956992
- scopus:85136343164
- ISSN
- 1420-3049
- DOI
- 10.3390/molecules27155040
- language
- English
- LU publication?
- yes
- id
- 859c3b33-68a5-4037-a727-255d7ef66ff2
- date added to LUP
- 2022-10-14 13:55:59
- date last changed
- 2024-07-26 00:34:45
@article{859c3b33-68a5-4037-a727-255d7ef66ff2, abstract = {{<p>Lactose plays a significant role in daily lives as a constituent of various food and pharmaceutical products. Yet, lactose intolerance conditions demand low-lactose and lactose-free products in the market. These increasing nutritional claims and labels on food products entail simple and reliable methods of analysis that can be used for meeting quality standards, nutritional claims and legal requirements. In this study, terahertz time–domain spectroscopy (THz-TDS) was employed to analyse α-lactose monohydrate qualitatively and quantitatively in food products. Both absorption spectra and absorption coefficient spectra were investigated for their prediction performance. Regression models for lactose quantification using peak area and height of the absorption peaks 0.53 and 1.37 THz were developed and assessed in infant formula samples. Satisfactory prediction results were achieved in ideal conditions with pure standards, but not in all predictions of infant formula samples. Reasons and further implications are discussed.</p>}}, author = {{Datta, Sopanant and Prasertsuk, Kiattiwut and Khammata, Nuttawat and Rattanawan, Patharakorn and Chia, Jia Yi and Jintamethasawat, Rungroj and Chulapakorn, Thawatchart and Limpanuparb, Taweetham}}, issn = {{1420-3049}}, keywords = {{lactose quantification; Terahertz time–domain spectroscopy; α-lactose monohydrate}}, language = {{eng}}, number = {{15}}, publisher = {{MDPI AG}}, series = {{Molecules}}, title = {{Terahertz Spectroscopic Analysis of Lactose in Infant Formula : Implications for Detection and Quantification}}, url = {{http://dx.doi.org/10.3390/molecules27155040}}, doi = {{10.3390/molecules27155040}}, volume = {{27}}, year = {{2022}}, }