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Terahertz Spectroscopic Analysis of Lactose in Infant Formula : Implications for Detection and Quantification

Datta, Sopanant ; Prasertsuk, Kiattiwut ; Khammata, Nuttawat ; Rattanawan, Patharakorn ; Chia, Jia Yi ; Jintamethasawat, Rungroj ; Chulapakorn, Thawatchart LU and Limpanuparb, Taweetham (2022) In Molecules 27(15).
Abstract

Lactose plays a significant role in daily lives as a constituent of various food and pharmaceutical products. Yet, lactose intolerance conditions demand low-lactose and lactose-free products in the market. These increasing nutritional claims and labels on food products entail simple and reliable methods of analysis that can be used for meeting quality standards, nutritional claims and legal requirements. In this study, terahertz time–domain spectroscopy (THz-TDS) was employed to analyse α-lactose monohydrate qualitatively and quantitatively in food products. Both absorption spectra and absorption coefficient spectra were investigated for their prediction performance. Regression models for lactose quantification using peak area and... (More)

Lactose plays a significant role in daily lives as a constituent of various food and pharmaceutical products. Yet, lactose intolerance conditions demand low-lactose and lactose-free products in the market. These increasing nutritional claims and labels on food products entail simple and reliable methods of analysis that can be used for meeting quality standards, nutritional claims and legal requirements. In this study, terahertz time–domain spectroscopy (THz-TDS) was employed to analyse α-lactose monohydrate qualitatively and quantitatively in food products. Both absorption spectra and absorption coefficient spectra were investigated for their prediction performance. Regression models for lactose quantification using peak area and height of the absorption peaks 0.53 and 1.37 THz were developed and assessed in infant formula samples. Satisfactory prediction results were achieved in ideal conditions with pure standards, but not in all predictions of infant formula samples. Reasons and further implications are discussed.

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author
; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
lactose quantification, Terahertz time–domain spectroscopy, α-lactose monohydrate
in
Molecules
volume
27
issue
15
article number
5040
publisher
MDPI AG
external identifiers
  • pmid:35956992
  • scopus:85136343164
ISSN
1420-3049
DOI
10.3390/molecules27155040
language
English
LU publication?
yes
id
859c3b33-68a5-4037-a727-255d7ef66ff2
date added to LUP
2022-10-14 13:55:59
date last changed
2024-06-13 20:09:44
@article{859c3b33-68a5-4037-a727-255d7ef66ff2,
  abstract     = {{<p>Lactose plays a significant role in daily lives as a constituent of various food and pharmaceutical products. Yet, lactose intolerance conditions demand low-lactose and lactose-free products in the market. These increasing nutritional claims and labels on food products entail simple and reliable methods of analysis that can be used for meeting quality standards, nutritional claims and legal requirements. In this study, terahertz time–domain spectroscopy (THz-TDS) was employed to analyse α-lactose monohydrate qualitatively and quantitatively in food products. Both absorption spectra and absorption coefficient spectra were investigated for their prediction performance. Regression models for lactose quantification using peak area and height of the absorption peaks 0.53 and 1.37 THz were developed and assessed in infant formula samples. Satisfactory prediction results were achieved in ideal conditions with pure standards, but not in all predictions of infant formula samples. Reasons and further implications are discussed.</p>}},
  author       = {{Datta, Sopanant and Prasertsuk, Kiattiwut and Khammata, Nuttawat and Rattanawan, Patharakorn and Chia, Jia Yi and Jintamethasawat, Rungroj and Chulapakorn, Thawatchart and Limpanuparb, Taweetham}},
  issn         = {{1420-3049}},
  keywords     = {{lactose quantification; Terahertz time–domain spectroscopy; α-lactose monohydrate}},
  language     = {{eng}},
  number       = {{15}},
  publisher    = {{MDPI AG}},
  series       = {{Molecules}},
  title        = {{Terahertz Spectroscopic Analysis of Lactose in Infant Formula : Implications for Detection and Quantification}},
  url          = {{http://dx.doi.org/10.3390/molecules27155040}},
  doi          = {{10.3390/molecules27155040}},
  volume       = {{27}},
  year         = {{2022}},
}