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Geosmin Attracts Aedes aegypti Mosquitoes to Oviposition Sites

Melo, Nadia LU ; Wolff, Gabriella H. ; Costa-da-Silva, Andre Luis ; Arribas, Robert ; Triana, Merybeth Fernandez LU ; Gugger, Muriel ; Riffell, Jeffrey A. ; DeGennaro, Matthew and Stensmyr, Marcus C. LU (2020) In Current Biology 30(1). p.5-134
Abstract

Geosmin is one of the most recognizable and common microbial smells on the planet. Some insects, like mosquitoes, require microbial-rich environments for their progeny, whereas for other insects such microbes may prove dangerous. In the vinegar fly Drosophila melanogaster, geosmin is decoded in a remarkably precise fashion and induces aversion, presumably signaling the presence of harmful microbes [1]. We have here investigated the effect of geosmin on the behavior of the yellow fever mosquito Aedes aegypti. In contrast to flies, geosmin is not aversive but mediates egg-laying site selection. Female mosquitoes likely associate geosmin with microbes, including cyanobacteria consumed by larvae [2], who also find geosmin—as well as... (More)

Geosmin is one of the most recognizable and common microbial smells on the planet. Some insects, like mosquitoes, require microbial-rich environments for their progeny, whereas for other insects such microbes may prove dangerous. In the vinegar fly Drosophila melanogaster, geosmin is decoded in a remarkably precise fashion and induces aversion, presumably signaling the presence of harmful microbes [1]. We have here investigated the effect of geosmin on the behavior of the yellow fever mosquito Aedes aegypti. In contrast to flies, geosmin is not aversive but mediates egg-laying site selection. Female mosquitoes likely associate geosmin with microbes, including cyanobacteria consumed by larvae [2], who also find geosmin—as well as geosmin-producing cyanobacteria—attractive. Using in vivo multiphoton calcium imaging from transgenic PUb-GCaMP6s mosquitoes, we show that Ae. aegypti code geosmin in a qualitatively similar fashion to flies, i.e., through a single olfactory channel with a high degree of sensitivity for this volatile. We further demonstrate that geosmin can be used as bait under field conditions, and finally, we show that geosmin, which is both expensive and difficult to obtain, can be substituted by beetroot peel extract, providing a cheap and viable potential mean for mosquito control and surveillance in developing countries.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Current Biology
volume
30
issue
1
pages
5 - 134
publisher
Elsevier
external identifiers
  • scopus:85077158650
  • pmid:31839454
ISSN
0960-9822
DOI
10.1016/j.cub.2019.11.002
language
English
LU publication?
yes
id
86238421-8a57-4fcc-86b3-450beafc81ce
date added to LUP
2020-01-10 11:01:17
date last changed
2020-11-16 04:57:23
@article{86238421-8a57-4fcc-86b3-450beafc81ce,
  abstract     = {<p>Geosmin is one of the most recognizable and common microbial smells on the planet. Some insects, like mosquitoes, require microbial-rich environments for their progeny, whereas for other insects such microbes may prove dangerous. In the vinegar fly Drosophila melanogaster, geosmin is decoded in a remarkably precise fashion and induces aversion, presumably signaling the presence of harmful microbes [1]. We have here investigated the effect of geosmin on the behavior of the yellow fever mosquito Aedes aegypti. In contrast to flies, geosmin is not aversive but mediates egg-laying site selection. Female mosquitoes likely associate geosmin with microbes, including cyanobacteria consumed by larvae [2], who also find geosmin—as well as geosmin-producing cyanobacteria—attractive. Using in vivo multiphoton calcium imaging from transgenic PUb-GCaMP6s mosquitoes, we show that Ae. aegypti code geosmin in a qualitatively similar fashion to flies, i.e., through a single olfactory channel with a high degree of sensitivity for this volatile. We further demonstrate that geosmin can be used as bait under field conditions, and finally, we show that geosmin, which is both expensive and difficult to obtain, can be substituted by beetroot peel extract, providing a cheap and viable potential mean for mosquito control and surveillance in developing countries.</p>},
  author       = {Melo, Nadia and Wolff, Gabriella H. and Costa-da-Silva, Andre Luis and Arribas, Robert and Triana, Merybeth Fernandez and Gugger, Muriel and Riffell, Jeffrey A. and DeGennaro, Matthew and Stensmyr, Marcus C.},
  issn         = {0960-9822},
  language     = {eng},
  number       = {1},
  pages        = {5--134},
  publisher    = {Elsevier},
  series       = {Current Biology},
  title        = {Geosmin Attracts Aedes aegypti Mosquitoes to Oviposition Sites},
  url          = {http://dx.doi.org/10.1016/j.cub.2019.11.002},
  doi          = {10.1016/j.cub.2019.11.002},
  volume       = {30},
  year         = {2020},
}