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Clinical Examinations of the Rectoanal Inhibitory Reflex Correlated with Anography Findings, Histopathological Findings, and Clinical Outcomes

Granéli, Christina LU ; Stenström, Pernilla LU orcid ; Börjesson, Anna LU and Arnbjörnsson, Einar LU (2014) In Surgery: Current Research 4(6).
Abstract
The diagnostic method for Hirschsprung’s disease (HD) involves rectal biopsy to determine the presence of

histopathological findings for aganglionosis. Contrast enema (CE) and anorectal manometry help to support the

indication for biopsies. Patients with HD lack a rectoanal inhibitory reflex (RAIR) that can be studied using manometry,

ultrasound, or a modified contrast enema (CE), which provokes the RAIR with an injection of cold fluid. A question that

arises is whether the RAIR also could be visualized with only a specific clinical examination.
Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Hirschsprung’s disease, Aganglionosis, Diagnostic, Rectoanal inhibitory reflex (RAIR), Radiology, Modified contrast enema, Clinical examination, Neonatal surgery
in
Surgery: Current Research
volume
4
issue
6
article number
1000213
publisher
OMICS Publishing Group
ISSN
2161-1076
DOI
10.4172/2161-1076.1000213
language
English
LU publication?
yes
id
d0d43c10-d36f-43c1-91b6-9bad3e0fd43d (old id 8626482)
date added to LUP
2016-04-01 13:25:47
date last changed
2025-04-04 13:58:46
@article{d0d43c10-d36f-43c1-91b6-9bad3e0fd43d,
  abstract     = {{The diagnostic method for Hirschsprung’s disease (HD) involves rectal biopsy to determine the presence of <br/><br>
histopathological findings for aganglionosis. Contrast enema (CE) and anorectal manometry help to support the <br/><br>
indication for biopsies. Patients with HD lack a rectoanal inhibitory reflex (RAIR) that can be studied using manometry, <br/><br>
ultrasound, or a modified contrast enema (CE), which provokes the RAIR with an injection of cold fluid. A question that <br/><br>
arises is whether the RAIR also could be visualized with only a specific clinical examination.}},
  author       = {{Granéli, Christina and Stenström, Pernilla and Börjesson, Anna and Arnbjörnsson, Einar}},
  issn         = {{2161-1076}},
  keywords     = {{Hirschsprung’s disease; Aganglionosis; Diagnostic; Rectoanal inhibitory reflex (RAIR); Radiology; Modified contrast enema; Clinical examination; Neonatal surgery}},
  language     = {{eng}},
  number       = {{6}},
  publisher    = {{OMICS Publishing Group}},
  series       = {{Surgery: Current Research}},
  title        = {{Clinical Examinations of the Rectoanal Inhibitory Reflex Correlated with Anography Findings, Histopathological Findings, and Clinical Outcomes}},
  url          = {{https://lup.lub.lu.se/search/files/3364305/8626815.pdf}},
  doi          = {{10.4172/2161-1076.1000213}},
  volume       = {{4}},
  year         = {{2014}},
}