Surface activity of tear fluid in patients with primary Sjögren's syndrome.
(2002) In Clinical Physiology and Functional Imaging 22(1). p.24-27- Abstract
- Rupture of the preocular tear film leads to formation of a dry spot on the cornea with ocular irritation and symptoms of dry eye. One of the factors determining the stability of the tear film is its surface activity. The purpose of this study was to examine the surface activity of tear fluid from patients with Sjögren's syndrome. Tear fluid was sampled from the eyes of 16 patients with primary Sjögren's syndrome. The surface activity of the sample was measured on a Wilhelmy balance. Maximum and minimum surface tension was 72·2 ± 1·7 and 52·9 ± 7·4 mN m-1, respectively. Corresponding values in a previously studied group of normal subjects were 71·5 ± 1·3 and 46·6 ± 3·8 mN m-1, respectively. The difference in minimal surface tension was... (More)
- Rupture of the preocular tear film leads to formation of a dry spot on the cornea with ocular irritation and symptoms of dry eye. One of the factors determining the stability of the tear film is its surface activity. The purpose of this study was to examine the surface activity of tear fluid from patients with Sjögren's syndrome. Tear fluid was sampled from the eyes of 16 patients with primary Sjögren's syndrome. The surface activity of the sample was measured on a Wilhelmy balance. Maximum and minimum surface tension was 72·2 ± 1·7 and 52·9 ± 7·4 mN m-1, respectively. Corresponding values in a previously studied group of normal subjects were 71·5 ± 1·3 and 46·6 ± 3·8 mN m-1, respectively. The difference in minimal surface tension was statistically significant (P<0·001). Reduced surface activity may be caused by dysfunction of the Meibomian glands and suggests a mechanism for causing the symptoms of dry eyes. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/115363
- author
- Zhao, Jiang ; Manthorpe, Rolf LU and Wollmer, Per LU
- organization
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Female, Human, Adolescent, Adult, Aged, Middle Age, Reference Values, Sjogren's Syndrome: metabolism, Support, Non-U.S. Gov't, Surface Tension, Tears: chemistry
- in
- Clinical Physiology and Functional Imaging
- volume
- 22
- issue
- 1
- pages
- 24 - 27
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000174885800007
- pmid:12003095
- scopus:0037069773
- ISSN
- 1475-0961
- DOI
- 10.1046/j.1475-097X.2002.00389.x
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Internal Medicine (013242500), Clinical Physiology (013242300), Clinical Physiology and Nuclear Medicine Unit (013242320), Department of Rheumatology (013036000)
- id
- 86389199-ea21-48ee-8005-8e2fd655608c (old id 115363)
- alternative location
- http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=12003095&dopt=AbstractPlus
- date added to LUP
- 2016-04-01 12:01:56
- date last changed
- 2023-09-01 16:39:55
@article{86389199-ea21-48ee-8005-8e2fd655608c, abstract = {{Rupture of the preocular tear film leads to formation of a dry spot on the cornea with ocular irritation and symptoms of dry eye. One of the factors determining the stability of the tear film is its surface activity. The purpose of this study was to examine the surface activity of tear fluid from patients with Sjögren's syndrome. Tear fluid was sampled from the eyes of 16 patients with primary Sjögren's syndrome. The surface activity of the sample was measured on a Wilhelmy balance. Maximum and minimum surface tension was 72·2 ± 1·7 and 52·9 ± 7·4 mN m-1, respectively. Corresponding values in a previously studied group of normal subjects were 71·5 ± 1·3 and 46·6 ± 3·8 mN m-1, respectively. The difference in minimal surface tension was statistically significant (P<0·001). Reduced surface activity may be caused by dysfunction of the Meibomian glands and suggests a mechanism for causing the symptoms of dry eyes.}}, author = {{Zhao, Jiang and Manthorpe, Rolf and Wollmer, Per}}, issn = {{1475-0961}}, keywords = {{Female; Human; Adolescent; Adult; Aged; Middle Age; Reference Values; Sjogren's Syndrome: metabolism; Support; Non-U.S. Gov't; Surface Tension; Tears: chemistry}}, language = {{eng}}, number = {{1}}, pages = {{24--27}}, publisher = {{John Wiley & Sons Inc.}}, series = {{Clinical Physiology and Functional Imaging}}, title = {{Surface activity of tear fluid in patients with primary Sjögren's syndrome.}}, url = {{https://lup.lub.lu.se/search/files/2751442/623799.pdf}}, doi = {{10.1046/j.1475-097X.2002.00389.x}}, volume = {{22}}, year = {{2002}}, }