Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

NURSES’ REPORTED TRAINING NEEDS FOR ADVANCED CELL THERAPIES : A SURVEY ON BEHALF OF THE NURSES GROUP OF THE EBMT

Kenyon, Michelle ; Liptrott, Sarah Jayne ; Kisch, Annika LU orcid ; Mooyaart, Jarl ; Piepenbroek, Brian ; Hutt, Daphna ; Salcedo, Isabel ; Ruggeri, Annalisa ; Chabannon, Cristian and Ellard, Rose , et al. (2024) In Clinical Hematology International 6(4). p.104-113
Abstract

BACKGROUND Advanced Therapy Medicinal Products (ATMPs) for human use have advanced globally with the rapid adoption of Chimeric Antigen Receptor T-cell (CAR-T) therapies in haemato-oncology. CAR-T cell therapy and ATMPs have unique, significant acute and chronic toxicities, and appropriate patient care is crucial. Significant challenges, including the need for nurse education and training, accompany optimal patient success and benefits. OBJECTIVES This study aimed to describe nurses’ training needs in relation to ATMP management and patient care. METHODS A cross-sectional online survey was performed by the European Society for Blood and Marrow Transplantation, based on a previously tested questionnaire developed in the UK. FINDINGS 109... (More)

BACKGROUND Advanced Therapy Medicinal Products (ATMPs) for human use have advanced globally with the rapid adoption of Chimeric Antigen Receptor T-cell (CAR-T) therapies in haemato-oncology. CAR-T cell therapy and ATMPs have unique, significant acute and chronic toxicities, and appropriate patient care is crucial. Significant challenges, including the need for nurse education and training, accompany optimal patient success and benefits. OBJECTIVES This study aimed to describe nurses’ training needs in relation to ATMP management and patient care. METHODS A cross-sectional online survey was performed by the European Society for Blood and Marrow Transplantation, based on a previously tested questionnaire developed in the UK. FINDINGS 109 complete responses from 86 different centers from 24 countries were returned (1207 distributed). Over 1/3 reported experience delivering licensed ATMPs (CAR-T). High-priority training areas included a general introduction to ATMPs, toxicity management, product-specific information, and regulatory frameworks for ATMPs. A clear need for ATMP-specific training exists and is regarded as important. Training prior to implementation is key and should be supported by ongoing competency maintenance. Counseling, patient support, and long-term follow-up are identified for future training and opportunities for nurse experience sharing in this rapidly evolving field.

(Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; ; ; ; and , et al. (More)
; ; ; ; ; ; ; ; ; and (Less)
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
ATMP, CAR-T, cellular therapy, education, gene therapy, nursing care
in
Clinical Hematology International
volume
6
issue
4
pages
10 pages
publisher
Saabron Press
external identifiers
  • scopus:85210149556
  • pmid:39564144
DOI
10.46989/001c.124593
language
English
LU publication?
yes
id
8706d170-8c5c-4b77-893f-c64233bfb153
date added to LUP
2025-01-15 16:46:25
date last changed
2025-07-17 07:54:09
@article{8706d170-8c5c-4b77-893f-c64233bfb153,
  abstract     = {{<p>BACKGROUND Advanced Therapy Medicinal Products (ATMPs) for human use have advanced globally with the rapid adoption of Chimeric Antigen Receptor T-cell (CAR-T) therapies in haemato-oncology. CAR-T cell therapy and ATMPs have unique, significant acute and chronic toxicities, and appropriate patient care is crucial. Significant challenges, including the need for nurse education and training, accompany optimal patient success and benefits. OBJECTIVES This study aimed to describe nurses’ training needs in relation to ATMP management and patient care. METHODS A cross-sectional online survey was performed by the European Society for Blood and Marrow Transplantation, based on a previously tested questionnaire developed in the UK. FINDINGS 109 complete responses from 86 different centers from 24 countries were returned (1207 distributed). Over 1/3 reported experience delivering licensed ATMPs (CAR-T). High-priority training areas included a general introduction to ATMPs, toxicity management, product-specific information, and regulatory frameworks for ATMPs. A clear need for ATMP-specific training exists and is regarded as important. Training prior to implementation is key and should be supported by ongoing competency maintenance. Counseling, patient support, and long-term follow-up are identified for future training and opportunities for nurse experience sharing in this rapidly evolving field.</p>}},
  author       = {{Kenyon, Michelle and Liptrott, Sarah Jayne and Kisch, Annika and Mooyaart, Jarl and Piepenbroek, Brian and Hutt, Daphna and Salcedo, Isabel and Ruggeri, Annalisa and Chabannon, Cristian and Ellard, Rose and Murray, John}},
  keywords     = {{ATMP; CAR-T; cellular therapy; education; gene therapy; nursing care}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{104--113}},
  publisher    = {{Saabron Press}},
  series       = {{Clinical Hematology International}},
  title        = {{NURSES’ REPORTED TRAINING NEEDS FOR ADVANCED CELL THERAPIES : A SURVEY ON BEHALF OF THE NURSES GROUP OF THE EBMT}},
  url          = {{http://dx.doi.org/10.46989/001c.124593}},
  doi          = {{10.46989/001c.124593}},
  volume       = {{6}},
  year         = {{2024}},
}